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World J Biol Chem. Mar 27, 2023; 14(2): 28-39
Published online Mar 27, 2023. doi: 10.4331/wjbc.v14.i2.28
Anticancer potential of Ferula assa-foetida and its constituents, a powerful plant for cancer therapy
Mohammad Amin Ghaffari Sirizi, Jalil Alizadeh Ghalenoei, Mohammad Allahtavakoli, Hasan Forouzanfar, Seyyed Majid Bagheri
Mohammad Amin Ghaffari Sirizi, Jalil Alizadeh Ghalenoei, Seyyed Majid Bagheri, Department of Physiology, Hematology-oncology Research Center, Shahid Sadoughi University of Medical Sciences, Yazd 8915173149, Iran
Mohammad Allahtavakoli, Department of Physiology and Pharmacology, School of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan 8915173149, Iran
Hasan Forouzanfar, Department of Nursing, Tabas School of nursing, Birjand University of Medical Sciences, Birjand 8915173149, Iran
Author contributions: Bagheri SM and Allahtavakoli M designed the research study; Sirizi MAG and Alizadeh Ghalenoei J analyzed the data and wrote the manuscript; Forouzanfar H contributed new reagents and analytic tools; Bagheri SM Final review and editing; All authors have read and approve the final manuscript.
Conflict-of-interest statement: All the author declare no conflict of interests for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Seyyed Majid Bagheri, PhD, Assistant Professor, Department of Physiology, Hematology-oncology Research Center, Shahid Sadoughi University of Medical Sciences, Yazd 8915173149, Iran. seyyedmajidbagheri@gmail.com
Received: November 10, 2022
Peer-review started: November 10, 2022
First decision: January 20, 2023
Revised: January 24, 2023
Accepted: February 21, 2023
Article in press: February 21, 2023
Published online: March 27, 2023
Processing time: 133 Days and 21.7 Hours
Core Tip

Core Tip: Finding new anti-cancer compounds is an important necessity in the treatment or prevention of this disease. Ferula assa-foetida has useful compounds for the prevention and treatment of cancer, which can be used in making new compounds. These compounds include sulphide compounds, flavonoids and terpene coumarins, which with new methods such as making emulsions and nanoparticles from these compounds can be of great help in reducing the costs of cancer patients and their life expectancy.