Efficacy of pantoprazole plus perforation repair for peptic ulcer and its effect on the stress response

Table 1 General information of patients with peptic ulcer in the two groups

Indicators	Control group (n = 50)	Research group (n = 58)	χ2/t	P value
Sex (male/female)	29/21	35/23	0.061	0.805
Age (yr)	49.10 ± 8.08	48.50 ± 7.21
Perforation site (stomach/duodenum/mixed)	22/20/8	20/27/11	1.025	0.599
History of alcoholism (with/without)	16/34	20/38	0.074	0.785
History of smoking (yes/no)	13/37	13/45	0.189	0.664

Table 2 Therapeutic effects in the two groups of patients with peptic ulcer

Indicators	Control group (n = 50)	Research group (n = 58)	χ2	P value
Marked response	22 (44.00)	30 (51.72)
Response	15 (30.00)	22 (37.93)
Nonresponse	13 (26.00)	6 (10.34)
Overall response	37 (74.00)	52 (89.66)	4.539	0.033

Table 3 Complications of patients with peptic ulcer in the two groups

Indicators	Control group (n = 50)	Research group (n = 58)	χ2	P value
Perforation	0 (0.00)	0 (0.00)
Hemorrhage	3 (6.00)	0 (0.00)
Pyloric obstruction	3 (6.00)	0 (0.00)
Total	6 (12.00)	0 (0.00)	7.369	0.007