Development of an innovative nomogram of risk factors to predict postoperative recurrence of gastrointestinal stromal tumors

Table 1 Differences between the demographic and clinical characteristics of the recurrence and nonrecurrence groups

Demographic characteristics	n (%)
	Recurrence (n = 13)	Nonrecurrence (n = 117)	Total (n = 130)
Age (yr)
< 60	8 (61.5)	62 (54.0)	70 (53.8)
≥ 60	5 (38.5)	55 (47.0)	60 (46.2)
Sex
Male	6 (46.2)	61 (52.1)	67 (51.5)
Female	7 (53.8)	56 (47.9)	63 (48.5)
Tumor site
Stomach	9 (69.2)	92 (78.6)	101 (77.7)
Small intestine	1 (7.7)	23 (19.7)	24 (18.5)
Large intestine	3 (23.1)	2 (1.7)	5 (3.8)
Tumor size
< 2 cm	2 (15.4)	25 (21.4)	27 (20.8)
≥ 2 and ≤ 5 cm	6 (46.1)	56 (47.9)	62 (47.7)
> 5 and ≤ 10 cm	1 (7.7)	30 (25.6)	31 (23.8)
> 10 cm	4 (30.8)	6 (5.1)	10 (7.7)
NIH risk category
Very low	3 (23.1)	31 (26.5)	34 (26.2)
Low	2 (15.4)	31 (26.5)	33 (25.4)
Middle	1 (7.7)	27 (23.1)	28 (21.5)
High	7 (53.8)	28 (23.9)	35 (26.9)
Mitotic rate
≤ 5 cm	7 (53.8)	87 (74.4)	94 (72.3)
> 5 cm and ≤ 10 cm	2 (15.4)	22 (18.8)	24 (18.5)
> 10 cm	4 (30.8)	8 (6.8)	12 (9.2)
Ki-67
< 5%	4 (30.8)	70 (59.8)	74 (56.9)
≥ 5%	9 (69.2)	47 (40.2)	56 (43.1)
Intratumoral hemorrhage
Yes	10 (76.9)	100 (85.5)	110 (84.6)
No	3 (23.1)	17 (14.5)	20 (15.4)
Intratumoral necrosis
Yes	8 (61.5)	99 (84.6)	107 (82.3)
No	5 (38.5)	18 (15.4)	23 (17.7)

NIH: National Institutes of Health.

Table 2 Prediction factors for recurrence of gastrointestinal stromal tumor

Intercept and variable	Prediction model
	β	Odds ratio (95%CI)	P value
Intercept	-3.0092	0.049 (0.006-0.245)	0.001
Mitotic rate	3.2152	24.907 (2.215-707.556)	0.020
Ki-67	0.7514	2.120 (0.340-15.083)	0.425
Intratumoral necrosis	-0.2675	0.765 (0.081-5.421)	0.799
Tumor size	-0.0147	0.985 (0.115-10.405)	0.989
Tumor site	3.4115	30.313 (3.265-405.088)	0.003
Age	0.1048	1.110 (0.228-5.611)	0.895

β: The regression coefficient.