Observational Study
Copyright ©The Author(s) 2018.
World J Gastrointest Surg. Feb 27, 2018; 10(2): 21-27
Published online Feb 27, 2018. doi: 10.4240/wjgs.v10.i2.21
Table 1 Patient characteristics
No resectionMinor resectionMajor resection
No. of patients41615
Gender (male:female)1:38:88:7
Age (yr)69 (56-76)75 (66-79)66 (50-74)
BMI (kg/m²)23.5 (21.4-28.6)24.7 (21.8-26.8)26.8 (25.2-28.7)
Weight (kg)64 (53-86)72 (63-83)78 (70-90)
ASA physical status (1/2:3/4)3:110:610:5
Preoperative bilirubin (µmol/L)5 (4-7)6 (5-10)7 (6-11)
Preoperative INR1.0 (0.9-1.0)1.0 (0.9-1.1)1.0 (1.0-1.1)
Diagnosis
Colorectal metastases31311
Other malignant tumors023
Benign tumors111
Number of hepatic tumors5 (1-7)1 (1-2)2 (2-6)
Largest hepatic tumor (mm)42 (17-57)30 (10-45)30 (23-51)
Preoperative chemotherapy2612
Oxaliplatin-based therapy249
Liver lobe operated (right lobe:left lobe:both lobes)-7:4:57:0:8
Operating time (h)2.5 (2-3)3 (3-5.5)6 (4.5-7)
Operative bleeding (mL)125 (100-150)275 (150-500)650 (400-1100)
Length of hospital stay (d)3 (2-6)6 (3-9)6 (5-7)
Liver parenchyma damage
Steatosis-01
Steatohepatitis-00
SOS-00
Table 2 Liver and spleen stiffness measurements for the minor and major resection groups
Minor resectionMajor resectionP value
No. of patients1615-
Future liver remnant (m/s)1.31 (1.15-1.52)1.41 (1.24-1.63)0.318
Right liver lobe preoperative (m/s)1.29 (1.12-1.49)1.38 (1.14-1.57)0.423
Left liver lobe preoperative (m/s)1.35 (1.06-1.71)1.41 (1.29-1.63)0.667
Spleen preoperative (m/s)2.76 (2.36-2.91)2.69 (2.33-3.11)0.984
Liver remnant postoperative (m/s)1.37 (1.12-1.77)2.20 (1.72-2.44)< 0.001
Spleen postoperative (m/s)2.83 (2.44-3.18)2.90 (2.63-3.50)0.216
Relative difference in liver remnant (%)4 (-16-24)42 (33-71)0.001
Relative difference in the spleen (%)2 (-1-13)16 (7-33)0.047