Observational Study
Copyright ©The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Feb 27, 2018; 10(2): 21-27
Published online Feb 27, 2018. doi: 10.4240/wjgs.v10.i2.21
Perioperative liver and spleen elastography in patients without chronic liver disease
Sam Eriksson, Hanna Borsiin, Carl-Fredrik Öberg, Hannes Brange, Zoran Mijovic, Christian Sturesson
Sam Eriksson, Hanna Borsiin, Carl-Fredrik Öberg, Hannes Brange, Christian Sturesson, Department of Surgery, Lund University, Skåne University Hospital, Lund S-221 85, Sweden
Zoran Mijovic, Department of Radiology, Lund University, Skåne University Hospital, Lund S-221 85, Sweden
Author contributions: Eriksson S contributed with methodology, data analysis, data presentation and writing of an original draft of the manuscript; Borsiin H, Öberg CF and Brange H contributed with project administration, data acquisition and data analysis; Mijovic Z contributed with methodology; Sturesson C contributed with conceptualization, methodology and supervision; all authors conducted critical revisions and approved the final version of the manuscript.
Institutional review board statement: The study was reviewed and approved by the Regional Ethical Review Board Lund.
Informed consent statement: All study participants provided informed written consent prior to study enrollment.
Conflict-of-interest statement: The authors have declared that no competing interests exist.
Data sharing statement: No additional data are available for sharing.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Christian Sturesson, MD, PhD, Associate Professor, Surgeon, Department of Surgery, Lund University, Skåne University Hospital, Lund S-221 85, Sweden. christian.sturesson@med.lu.se
Telephone: +46-46-172347 Fax: +46-46-172335
Received: November 2, 2017
Peer-review started: November 2, 2017
First decision: December 6, 2017
Revised: January 14, 2018
Accepted: February 6, 2018
Article in press: February 6, 2018
Published online: February 27, 2018
Processing time: 115 Days and 20.6 Hours
Core Tip

Core tip: Point shear-wave elastography is an ultrasound-based technique which lets the user measure tissue stiffness. The technique has previously mostly been used to study patients with chronic liver disease and cirrhosis. In the current study we investigate changes in liver and spleen stiffness in patients without chronic liver disease undergoing chemotherapy and liver resection for liver tumors. A major liver resection resulted in a 42% increase in liver stiffness. Also, spleen stiffness increased more after a major than after a minor resection. However, there was no difference in tissue stiffness between patients who received preoperative chemotherapy or not.