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World J Gastrointest Surg. Apr 27, 2013; 5(4): 83-96
Published online Apr 27, 2013. doi: 10.4240/wjgs.v5.i4.83
Published online Apr 27, 2013. doi: 10.4240/wjgs.v5.i4.83
Computed tomography-based diagnostics might be insufficient in the determination of pancreatic cancer unresectability
Vyacheslav I Egorov, Department of Surgical Oncology, Ostroumov 14th City Hospital, Sechenov First State Medical University, 119048 Moscow, Russia
Roman V Petrov, Department of Surgical Oncology, Ostroumov 14th City Hospital, 119048 Moscow, Russia
Elena N Solodinina, Natalia A Kuruschkina, Department of Endoscopy, Vishnevsky Institute of Surgery, 117997 Moscow, Russia
Gregory G Karmazanovsky, Natalia S Starostina, Department of Radiology, Vishnevsky Institute of Surgery, 117997 Moscow, Russia
Author contributions: Egorov VI contributed to concept and design of the paper; Egorov VI, Petrov RV and Starostina NS contributed to surgery and follow-up; Karmazanovsky GG and Starostina NS contributed to imaging; Solodinina EN and Kuruschkina NA contributed to endoscopy and endoUS; all the authors contributed to data acquisition/interpretation, literature research, drafting the manuscript, revision and final version approval.
Correspondence to: Dr. Vyacheslav I Egorov, Department of Surgical Oncology, Ostroumov 14th City Hospital, Sechenov First State Medical University, 2, Building 2, Bolshaya Pirogovskaya Str., 119048 Moscow, Russia. v.egorov61@gmail.com
Telephone: +7-926-7359511 Fax: +7-926-7359511
Received: November 22, 2012
Revised: February 9, 2013
Accepted: February 28, 2013
Published online: April 27, 2013
Revised: February 9, 2013
Accepted: February 28, 2013
Published online: April 27, 2013
Core Tip
Core Tip: Pancreatic cancer remains one of the most aggressive neoplastic processes, and the methods to manage it are constantly evolving. Resection remains the only potential cure for pancreatic cancer, and it can prolong survival in patients compared to those who do not undergo resection. However, only a minority of patients are candidates for surgery at diagnosis, and only a minority of patients who undergo surgery survive beyond 5 years. The most important cause of an inacurate assessment of resectability is underestimation of vascular invasion. This study attempted to address the other side of the problem: overestimation of arterial involvement in patients with pancreatic cancer.