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©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Sep 27, 2024; 16(9): 2808-2814
Published online Sep 27, 2024. doi: 10.4240/wjgs.v16.i9.2808
Published online Sep 27, 2024. doi: 10.4240/wjgs.v16.i9.2808
Serum tumor markers (carcinoembryonic antigen, carbohydrate antigen 19-9, carbohydrate antigen 72-4, carbohydrate antigen 24-2, ferritin) and gastric cancer prognosis correlation
Jie-Wen Zhu, Ling-Zhen Gong, Qian-Wen Wang, Department of Clinical Laboratory, Huangshi Central Hospital (Affiliated Hospital of Hubei Polytechnic University), Hubei Key Laboratory of Kidney Disease Pathogenesis and Intervention, Huangshi Tumor Molecular Diagnosis and Treatment Key Laboratory, Huangshi 435000, Hubei Province, China
Co-first authors: Jie-Wen Zhu and Ling-Zhen Gong.
Author contributions: Zhu JW, Gong LZ, Wang QW contributed equally to this work; Zhu JW, Gong LZ designed the research study, performed the primary literature and data extraction, analyzed the data and wrote the manuscript; Zhu JW, Gong LZ, Wang QW were responsible for revising the manuscript for important intellectual content; All authors read and approved the final version.
Institutional review board statement: The study was reviewed and approved by the Huangshi central hospital Institutional Review Board [Approval No. 2021(90)].
Informed consent statement: All study participants or their legal guardian provided informed written consent about personal and medical data collection prior to study enrolment.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
Data sharing statement: Technical appendix, statistical code, and dataset available from the corresponding author at
STROBE statement: The authors have read the STROBE Statement—a checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-a checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Qian-Wen Wang, Technologist in charge, Bachelor’s degree, Department of Clinical Laboratory, Huangshi Central Hospital, (Affiliated Hospital of Hubei Polytechnic University), Hubei Key Laboratory of Kidney Disease Pathogenesis and Intervention, Huangshi Tumor Molecular Diagnosis and Treatment Key Laboratory, No. 293 Hospital Street, Xisai District, Huangshi 435000, Hubei Province, China.
Received: May 10, 2024
Revised: July 2, 2024
Accepted: July 22, 2024
Published online: September 27, 2024
Processing time: 130 Days and 13.5 Hours
Revised: July 2, 2024
Accepted: July 22, 2024
Published online: September 27, 2024
Processing time: 130 Days and 13.5 Hours
Core Tip
Core Tip: In this study, the aim is to establish a scientific basis for tailoring personalized treatment strategies and evaluating the prognosis of individuals affected by gastric cancer. This study demonstrates a significant association between the expression levels of serum tumor markers carcinoembryonic antigen, carbohydrate antigen (CA) 19-9, CA72-4, CA24-2 and ferritin in patients with gastric cancer and their prognosis. These markers can serve as important indicators for prognostic evaluation of gastric cancer. Notably, abnormally elevated initial marker levels may aid in identifying gastric cancer patients with poor prognosis.