Editorial
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Feb 27, 2024; 16(2): 260-265
Published online Feb 27, 2024. doi: 10.4240/wjgs.v16.i2.260
Actuality and underlying mechanisms of systemic immune-inflammation index and geriatric nutritional risk index prognostic value in hepatocellular carcinoma
Konstantin Y Tchilikidi
Konstantin Y Tchilikidi, Department of Surgery with Postgraduate Education, Altai State Medical University, Barnaul 656031, Russia
Author contributions: Tchilikidi KY is the sole author of this manuscript, and contributed to every process of this article.
Conflict-of-interest statement: The author has no relevant conflicting interests to declare.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Konstantin Y Tchilikidi, MD, Assistant Professor, Department of Surgery with Postgraduate Education, Altai State Medical University, Krasnoarmeysky Avenue 131-10, Barnaul 656031, Russia. kt80876@gmail.com
Received: November 3, 2023
Peer-review started: November 3, 2023
First decision: December 18, 2023
Revised: December 26, 2023
Accepted: February 3, 2024
Article in press: February 3, 2024
Published online: February 27, 2024
Processing time: 114 Days and 12.2 Hours
Core Tip

Core Tip: The systemic immune-inflammation index and geriatric nutritional risk index have significant survival predictive value in both palliative treatment and radical surgery settings. The underlying mechanisms of their possible predictive properties lie in the field of essential cancer features. Those features provide tumor nutrition, growth, and distribution throughout the body, such as vascular invasion. On the other hand, they are associated with the ability of patients to resist tumor progression and development of complications in both postoperative and cancer-related settings. The article is of considerable interest. It would be helpful to continue the study follow-up for 2 years or longer.