Retrospective Study
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Nov 27, 2023; 15(11): 2513-2524
Published online Nov 27, 2023. doi: 10.4240/wjgs.v15.i11.2513
Application of CD34 expression combined with three-phase dynamic contrast-enhanced computed tomography scanning in preoperative staging of gastric cancer
Hua Liu, Kang-Yan Zhao
Hua Liu, Department of Pathology, The First People's Hospital of Lianyungang, Lianyungang 222000, Jiangsu Province, China
Kang-Yan Zhao, Department of Radiology, Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Sciences, Xiangyang 441021, Hubei Province, China
Author contributions: Liu H designed the study and wrote the paper; Zhao KY designed the study and reviewed the manuscript; all authors annotated the manuscript.
Institutional review board statement: This study was reviewed and approved by the Ethics Committee of The First People's Hospital of Lianyungang.
Informed consent statement: This study is a retrospective study and used anonymous patients data from the past and did not pose any risks to patients, we have applied for exemption from informed consent.
Conflict-of-interest statement: We have no financial relationships to disclose.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Kang-Yan Zhao, MM, Attending Doctor, Department of Radiology, Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Sciences, No. 136 Jingzhou Street, Xiangcheng District, Xiangyang 441021, Hubei Province, China. zkyhdz@163.com
Received: September 19, 2023
Peer-review started: September 19, 2023
First decision: October 8, 2023
Revised: October 26, 2023
Accepted: November 3, 2023
Article in press: November 3, 2023
Published online: November 27, 2023
Processing time: 69 Days and 1.9 Hours
Core Tip

Core Tip: We evaluated the value of CD34 expression combined with dynamic three-phase enhanced computed tomography (CT) scanning in the preoperative staging and invasion evaluation of gastric cancer (GC). This study demonstrated that the diagnostic accuracy of dynamic three-phase enhanced CT scanning for the T stage and the N stage was 68.00%-79.41% and 74.07%-85.00% respectively, and the addition of CD34-marked microvessel density improved the diagnostic efficiency. This combination can be used as a reliable basis to preoperatively assess the invasion depth and lymph node metastasis of GC and provide guidance for surgical treatment.