Retrospective Study
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Sep 27, 2022; 14(9): 986-996
Published online Sep 27, 2022. doi: 10.4240/wjgs.v14.i9.986
Study of preoperative diagnostic modalities in Chinese patients with superficial esophageal squamous cell carcinoma
Ya-Ting Zeng, Yu-Ying Sun, Wen-Cheng Tan, Shu-Ai Luo, Bi-Hui Zou, Guang-Yu Luo, Chun-Yu Huang
Ya-Ting Zeng, Yu-Ying Sun, Wen-Cheng Tan, Shu-Ai Luo, Bi-Hui Zou, Guang-Yu Luo, Chun-Yu Huang, State Key Laboratory of Oncology in South China, Sun Yat-sen University Cancer Center, Guangzhou 510060, Guangdong Province, China
Ya-Ting Zeng, Yu-Ying Sun, Wen-Cheng Tan, Shu-Ai Luo, Bi-Hui Zou, Guang-Yu Luo, Chun-Yu Huang, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou 510060, Guangdong Province, China
Ya-Ting Zeng, Wen-Cheng Tan, Shu-Ai Luo, Bi-Hui Zou, Guang-Yu Luo, Chun-Yu Huang, Department of Endoscopy, Sun Yat-sen University Cancer Center, Guangzhou 510060, Guangdong Province, China
Yu-Ying Sun, Cancer Prevention Center, Sun Yat-sen University Cancer Center, Guangzhou 510060, Guangdong Province, China
Author contributions: Zeng Y designed and performed the study and wrote the manuscript; Sun Y and Huang C contributed to the conception of the study; Tan W and Luo G helped perform the analysis with constructive discussions; Luo S and Zhou B collected the data;
Supported by the Guangdong Esophageal Cancer Institute Science and Technology Program, No. M202013.
Institutional review board statement: This study was approved by the Ethics Committee of the Sun Yat-Sen University Cancer Center.
Informed consent statement: Informed consent from patients was waived by the Ethics Committee of the Sun Yat-Sen University Cancer Center.
Conflict-of-interest statement: All authors report no relevant conflict of interest for this article.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Chun-Yu Huang, MD, PhD, Professor, State Key Laboratory of Oncology in South China, Sun Yat-sen University Cancer Center, No. 651 Dongfeng East Road, Guangzhou 510060, Guangdong Province, China. huangchy@sysucc.org.cn
Received: June 9, 2022
Peer-review started: June 9, 2022
First decision: August 1, 2022
Revised: August 11, 2022
Accepted: September 8, 2022
Article in press: September 8, 2022
Published online: September 27, 2022
Processing time: 105 Days and 0.2 Hours
Core Tip

Core Tip: Endoscopic ultrasonography (EUS) and magnifying endoscopy (ME) reliably determine indications for endoscopic resection in patients with superficial esophageal squamous cell carcinoma (SESCC). ME is a widely accepted method for predicting the invasion depth. However, the addition of EUS is controversial. We retrospectively analyzed Chinese patients with suspected SESCC who completed both ME and EUS and underwent resection at our facility. We found that EUS and ME demonstrated comparable accuracy and EUS can compensate for deficiencies inherent to ME in some cases. The miniature probe was best suited for detecting early-stage lesions. These findings may further improve diagnostic accuracy.