Meta-Analysis
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Sep 27, 2022; 14(9): 1060-1071
Published online Sep 27, 2022. doi: 10.4240/wjgs.v14.i9.1060
Laparoscopic appendectomy, stump closure and endoloops: A meta-analysis
Noemi Zorzetti, Augusto Lauro, Maria Irene Bellini, Samuele Vaccari, Barbara Dalla Via, Maurizio Cervellera, Roberto Cirocchi, Salvatore Sorrenti, Vito D’Andrea, Valeria Tonini
Noemi Zorzetti, Department of General Surgery, Ospedale Civile A Costa, Porretta Terme 40046, Italy
Noemi Zorzetti, Augusto Lauro, Maria Irene Bellini, Samuele Vaccari, Salvatore Sorrenti, Vito D’Andrea, Department of Surgical Sciences, Sapienza University, Rome 00161, Italy
Samuele Vaccari, Department of General Surgery, Ospedale di Bentivoglio, Bologna 40010, Italy
Barbara Dalla Via, Valeria Tonini, Department of Emergency Surgery, St Orsola University Hospital, Bologna 40138, Italy
Maurizio Cervellera, Department of General Surgery, Ospedale Santissima Annunziata, Taranto 74121, Italy
Roberto Cirocchi, Department of General Surgery, Ospedale di Terni, Università di Perugia, Terni 05100, Italy
Author contributions: Zorzetti L and Bellini MI wrote and revised the article; Lauro A, Dalla Via B, Cervellera M, Tonini V, Sorrenti S, Cirocchi R and D’Andrea V designed the research study; Vaccari S, Zorzetti N, Lauro A, and Bellini MI performed the research; and all authors have read and approve the final manuscript.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Maria Irene Bellini, MD, PhD, Assistant Professor, Senior Lecturer, Department of Surgical Sciences, Sapienza University, Viale Regina Elena, Rome 00161, Italy. mariairene.bellini@uniroma1.it
Received: April 21, 2022
Peer-review started: April 21, 2022
First decision: July 14, 2022
Revised: July 22, 2022
Accepted: August 19, 2022
Article in press: August 19, 2022
Published online: September 27, 2022
Processing time: 153 Days and 18.4 Hours
Core Tip

Core Tip: Stump closure in the acute appendectomy setting could be performed via endoloop (EL) or endostapler use. The present meta-analysis assesses the experience of 996 patients consecutively treated in the department of Emergency General Surgery - St Orsola University Hospital, Bologna (Italy) and the evidence published in literature, confirming there is no superiority of a surgical method on how to perform the stump closure, with regards to wound infections, abdominal abscess, and total post-operative complications. Even when acute appendicitis is complicated, the routine use of EL is safe in most patients.