Matsuda Y, Yano M, Miyoshi N, Noura S, Ohue M, Sugimura K, Motoori M, Kishi K, Fujiwara Y, Gotoh K, Marubashi S, Akita H, Takahashi H, Sakon M. Solitary mediastinal lymph node recurrence after curative resection of colon cancer. World J Gastrointest Surg 2014; 6(8): 164-168 [PMID: 25161766 DOI: 10.4240/wjgs.v6.i8.164]
Corresponding Author of This Article
Masahiko Yano, MD, PhD, Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Disease, 1-3-3 Nakamichi, Higashinari-ku, Osaka 537-8511, Japan. yano-ma@mc.pref.osaka.jp
Research Domain of This Article
Surgery
Article-Type of This Article
Case Report
Open-Access Policy of This Article
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Yasuhiro Matsuda, Masahiko Yano, Norikatsu Miyoshi, Shingo Noura, Masayuki Ohue, Keijiro Sugimura, Masaaki Motoori, Kentaro Kishi, Yoshiyuki Fujiwara, Kunihito Gotoh, Shigeru Marubashi, Hirofumi Akita, Hidenori Takahashi, Masato Sakon, Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Disease, Osaka 537-8511, Japan
Author contributions: Matsuda Y and Yano M designed the report; Miyoshi N, Noura S, Ohue M, Sugimura K, Motoori M and Sakon M made a decision of the treatment; Kishi K, Fujiwara Y, Gotoh K, Marubashi S, Akita H and Takahashi H collected the patient’s clinical data; Matsuda Y and Yano M analyzed the data and wrote the paper.
Supported by Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Disease, Osaka 537-8511, Japan
Correspondence to: Masahiko Yano, MD, PhD, Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Disease, 1-3-3 Nakamichi, Higashinari-ku, Osaka 537-8511, Japan. yano-ma@mc.pref.osaka.jp
Telephone: +81-6-69721181 Fax: +81-6-69818055
Received: February 26, 2014 Revised: March 27, 2014 Accepted: July 18, 2014 Published online: August 27, 2014 Processing time: 182 Days and 4.2 Hours
Abstract
We report two cases of solitary mediastinal lymph node recurrence after colon cancer resection. Both cases had para-aortic lymph node metastasis at the time of initial surgery and received adjuvant chemotherapy for 4 years in case 1 and 18 mo in case 2. The time to recurrence was more than 8 years in both cases. After resection of the recurrent tumor, the patient is doing well with no recurrence for 6 years in case 1 and 4 mo in case 2. Patients should be followed up after colon cancer surgery considering the possibility of solitary mediastinal lymph node recurrence if they had para-aortic node metastasis at the time of initial surgery.
Core tip: The first site of recurrence of colon cancer is rarely the mediastinal lymph nodes, and solitary recurrence at this site without another site of recurrence is extremely rare. The operative indication and prognostic significance of the resection of mediastinal lymph node metastasis has not been determined because such recurrence is very rare. Patients should be followed up after colon cancer surgery considering the possibility of solitary mediastinal lymph node recurrence if they had para-aortic node metastasis at the time of initial surgery.
