Published online Feb 27, 2024. doi: 10.4240/wjgs.v16.i2.491
Peer-review started: November 21, 2023
First decision: December 12, 2023
Revised: December 23, 2023
Accepted: January 12, 2024
Article in press: January 12, 2024
Published online: February 27, 2024
Processing time: 96 Days and 1.8 Hours
Transjugular intrahepatic portosystemic shunt (TIPS) placement is a procedure that can effectively treat complications of portal hypertension, such as variceal bleeding and refractory ascites. However, there have been no specific studies on predicting long-term survival after TIPS placement.
To establish a model to predict long-term survival in patients with hepatitis cirrhosis after TIPS.
A retrospective analysis was conducted on a cohort of 224 patients who un
The indication (variceal bleeding or ascites), shunt reasonability (reasonable or unreasonable), ICGR15, post
The NDC model can accurately predict long-term survival after the TIPS procedure in patients with hepatitis cirrhosis, help identify high-risk patients and guide follow-up management after TIPS implantation.
Core Tip: The core finding of this article is that a newly developed Cox regression model (NDC) outperforms the existing scoring models, such as the Child-Pugh, model for end-stage liver disease (MELD), MELD-sodium and the Freiburg index of post-transjugular intrahepatic portosystemic shunt (TIPS) survival, in predicting long-term survival after TIPS placement in patients with hepatitis cirrhosis. In the NDC model, considered factors such as indication for TIPS, shunt reasonability, indocyanine green retention rate at 15 min, post-portal venous pressure gradient, percentage decrease in portal venous pressure, and total bilirubin are considered. It provided a more accurate prediction of 6-year survival, allowing for the identification of high-risk patients who may need closer follow-up after the procedure.