Published online Jan 27, 2024. doi: 10.4240/wjgs.v16.i1.59
Peer-review started: October 30, 2023
First decision: November 8, 2023
Revised: December 6, 2023
Accepted: December 18, 2023
Article in press: December 18, 2023
Published online: January 27, 2024
Severe acute pancreatitis (SAP), a condition with rapid onset, critical condition and unsatisfactory prognosis, poses a certain threat to human health, warranting optimization of relevant treatment plans to improve treatment efficacy.
To evaluate the efficacy and safety of computerized tomography-guided the
Forty-two SAP patients admitted to The Second Affiliated Hospital of Fujian Medical University from June 2020 to June 2023 were selected. On the basis of routine treatment, 20 patients received SS therapy (control group) and 22 patients were given CT-TPPCD plus SS intervention (research group). The efficacy, safety (pancreatic fistula, intra-abdominal hemorrhage, sepsis, and organ dysfunction syndrome), abdominal bloating and pain relief time, bowel recovery time, hospital stay, inflammatory indicators (C-reactive protein, interleukin-6, and pro
Compared with the control group, the research group had a markedly higher total effective rate, faster abdominal bloating and pain relief and bowel recovery, shorter hospital length of stay, fewer complications, and lower posttreatment inflammatory indices and APACHE-II scores.
CT-TPPCD in combination with SS is effective for SAP patients, which can reduce complications, accelerate symptom resolution, inhibit inflammation, and improve patient condition, with promising prospects for clinical promotion.
Core Tip: Severe acute pancreatitis (SAP) is a severe acute manifestation of pancreatitis, which may lead to disease deterioration due to local and systemic infections. Therefore, an effective and safe intervention method is urgently needed to optimize the management of SAP patients. This study suggests that computerized tomography-guided therapeutic percutaneous puncture catheter drainage combined with somatostatin for SAP patients has high clinical efficacy and safety, providing a novel option for the clinical management optimization of such patients.