Prevalence of type 2 diabetes mellitus in the pediatric population of a third-level care hospital in Mexico City in 2013 and 2018

doi:10.4239/wjd.v14.i3.290

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Mar 15, 2023 (publication date) through Dec 26, 2024

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World Journal of Diabetes

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1948-9358

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Diabetes. Mar 15, 2023; 14(3): 290-298
Published online Mar 15, 2023. doi: 10.4239/wjd.v14.i3.290

Table 1 Clinical and biochemical characteristics of patients with type 2 diabetes

Variable	Patients with T2DM (2013)	Patients with T2DM (2018)	P value
Variable	n = 47	n = 104	P value
Sex [H (%)]	26 (55.3)	34 (32.7)	0.009
Age (yr)^a	12.96 ± 1.9	14.6 ± 1.9	0.000
Weight (kg)	62.6 ± 20.4	62.8 ± 19.4	0.956
Height (cm)	157.5 ± 14.2	156.9 ± 11.9	0.773
BMI (kg/m²)^a	25.3 ± 5.3	24.4 ± 6.7	0.170
Waist (cm)^a	84.7 ± 14.2	84.5 ± 19.2	0.905
Cholesterol total (mg/dL)	163.4 ± 33.1	172.5 ± 39.8	0.172
HDL-C (mg/dL)^a	40.7 ± 12.1	44.1 ± 8.6	0.087
LDL-C (mg/dL)^a	100.0 ± 25.3	95.9 ± 31.3	0.436
Triglycerides (mg/dL)^a	136.7 ± 92.0	147.7 ± 64.9	0.412
AST (U/L)^b	22.0 (11-143)	23.0 (11-89)	0.403
ALT (U/L)^b	43.0 (23-139)	36.0 (11-79)	0.005
Fasting glucose (mg/dL)^a	150.9 ± 88.1	189.0 ± 109.2	0.038
HbA1c (%)^a	10.5 ± 3.9	8.9 ± 2.8	0.069
Fasting insulin (mUI/mL)^b	11.2 (2-71)	11.2 (2-80)	0.902
C-peptide (ng/dL)^b	2.0 (0.09-8.0)	1.5 (0.1-8.5)	0.014
SBP (mmHg)^b	95.8 (70-130)	110 (90-150)	0.004
DBP (mmHg)^b	62.8 (48-85)	70.0 (60-90)	0.005
HOMA-β^b	135.9 (23-160.9)	50.2 (16-145)	0.183

^amean ± SD.

^bMedian (interquartile ranges).

T2DM: Type 2 diabetes mellitus; BMI: Body mass index; HDL-C: HDL cholesterol; LDL-C: LDL cholesterol; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; HbA1c: Hemoglobin A1c; SBP: Systolic blood pressure; DBP: Diastolic blood pressure; HOMA-IR: Homeostatic Model of Assessment-Insulin Resistance.

Table 2 Family member and perinatal antecedents in the two study groups, n (%)

Variable	Patients with T2DM (2013)	Patients with T2DM (2018)	P value
Variable	n = 47	n = 104	P value
History of T2DM, in relatives of 1° and 2° [n (%)]	24 (51.1)	79 (75.9)	0.002
Antecedent of obesity in relatives of 1° and 2° [n (%)]	31 (65.9)	84 (80.7)	0.048
Antecedent of DM [n (%)]	7 (14.9)	9 (8.7)	0.249
Weight at birth (kg)	3.31 ± 0.66	3.03 ± 0.44	0.005
Socioeconomic status^a^,^b
Upper	5 (10.6)	6 (5.8)
Upper-middle	6 (12.8)	6 (5.8)
Middle	6 (12.8)	18 (17.3)	0.023
Lower-middle	16 (34)	18 (17.3)
Upper-Lower	10 (21.3)	28 (26.9)
Lower	4 (8.5)	28 (26.9)
Comorbidities
Hypercholesterolemia [n (%)]	22 (46.8)	29 (27.9)	0.023
Hypertriglyceridemia	27 (57.4)	78 (75.0)	0.030
Hypoalphalipoproteinemia	19 (40.4)	16 (15.4)	0.001
Hepatic steatosis	6 (12.8)	22 (21.2)	0.219
Arterial hypertension	5 (10.6)	22 (22.3)	0.021

^aAMAI/NSE 8 × 7 model.

^bPearson χ² test.

T2DM: Type 2 diabetes mellitus.

Citation: Molina-Díaz JM, Vargas-Terrez BE, Medina-Bravo PG, Martínez-Ambrosio A, Miranda-Lora AL, Klünder-Klünder M. Prevalence of type 2 diabetes mellitus in the pediatric population of a third-level care hospital in Mexico City in 2013 and 2018. World J Diabetes 2023; 14(3): 290-298
URL: https://www.wjgnet.com/1948-9358/full/v14/i3/290.htm
DOI: https://dx.doi.org/10.4239/wjd.v14.i3.290