Copyright
©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
Prevalence of type 2 diabetes mellitus in the pediatric population of a third-level care hospital in Mexico City in 2013 and 2018
Jorge Mario Molina-Díaz, Blanca Estela Vargas-Terrez, Patricia Guadalupe Medina-Bravo, Antonia Martínez-Ambrosio, América Liliana Miranda-Lora, Miguel Klünder-Klünder
Jorge Mario Molina-Díaz, Department of Child Endocrinology, Children’s Hospital Federico Gomez, Autonomous University of Mexico, Mexico City 06250, Mexico
Blanca Estela Vargas-Terrez, Faculty of Business, La Salle University, Mexico City 06250, Mexico
Patricia Guadalupe Medina-Bravo, Department of Endocrinology, Children’s Hospital Federico Gomez, Mexico City 06720, Mexico
Antonia Martínez-Ambrosio, Department of Nursing and Endocrinology, Children’s Hospital Federico Gómez, Mexico City 06720, Mexico
América Liliana Miranda-Lora, Epidemiological Research Unit in Endocrinology and Nutrition, Children’s Hospital Federico Gomez, Mexico City 06720, Mexico
Miguel Klünder-Klünder, Division of Research, Children’s Hospital Federico Gomez, Mexico City 06720, Mexico
Author contributions: Molina JM and Vargas BE conceptualized and wrote the initial manuscript; Martínez A and Medina PG critically reviewed the manuscript; Miranda AL and Klünder M edited the manuscript; Molina JM finalized the manuscript.
Institutional review board statement: This study was authorized by the ethics and research committee of the Federico Gomez Children's Hospital of Mexico.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: All the authors declare they have no conflict of interest to disclose.
Data sharing statement: No additional data are available.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
https://creativecommons.org/Licenses/by-nc/4.0/ Corresponding author: Jorge Mario Molina-Díaz, PhD, Doctor, Department of Child Endocrinology, Children’s Hospital Federico Gomez, Autonomous University of Mexico, Mexico City 06250, Mexico. dereck79@live.com.mx
Received: November 15, 2022
Peer-review started: November 15, 2022
First decision: January 3, 2023
Revised: January 15, 2023
Accepted: February 14, 2023
Article in press: February 14, 2023
Published online: March 15, 2023
Processing time: 120 Days and 14.4 Hours
ARTICLE HIGHLIGHTS
Research background
This study is part of a line of research at the Federico Gómez Children's Hospital of Mexico on the behavior of type 2 diabetes in the child population.
Research motivation
Because Mexico is a country with a high prevalence of diabetes and obesity, which unfortunately extends to the pediatric population, knowing the behavior of this disease in this specific age group will allow determining actions in clinical practice as well as in health policies.
Research objectives
To show the prevalence of type 2 diabetes in children and adolescents in two different time periods, as well as its clinical and biochemical characteristics.
Research methods
This is a cross-sectional study of children and adolescents from the Diabetes Clinic at the Children’s Hospital, Hospital Infantil de México Federico Gómez, that compared two periods in the time.
Research results
An increase in the prevalence was observed, as well as a much more aggressive phenotype, which could lead to chronic complications in a shorter period.
Research conclusions
The rates of type 2 diabetes mellitus (T2DM) increased significantly from 2013 to 2018, having an early onset in children and adolescents, as well as a more aggressive phenotype; in other words, patients tended to be more obese and have more lipid alterations, which can lead to worse metabolic control, greater chronic complications, and significantly higher risk of death due to cardiovascular causes or ischemic events. Therefore, T2DM in the pediatric population definitely presents with a more aggressive phenotype and worse prognosis over the long term.
Research perspectives
We will continue with the follow-up of these patients to determine the behavior of the disease and have communication with the first and second level care centers to refer the patients in a timely manner.
