Observational Study
Copyright ©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Jan 15, 2017; 8(1): 18-27
Published online Jan 15, 2017. doi: 10.4239/wjd.v8.i1.18
Clinical and dietary predictors of common carotid artery intima media thickness in a population with type 1 and type 2 diabetes: A cross-sectional study
Kristina S Petersen, Jennifer B Keogh, Peter J Meikle, Manohar L Garg, Peter M Clifton
Kristina S Petersen, Jennifer B Keogh, Peter M Clifton, School of Pharmacy and Medical Sciences, University of South Australia, Adelaide, SA 5000, Australia
Peter J Meikle, Baker IDI Heart and Diabetes Institute, Melbourne, VIC 3004, Australia
Manohar L Garg, Nutraceuticals Research Group, University of Newcastle, Callaghan, NSW 2308, Australia
Author contributions: Keogh JB and Clifton PM designed the research (project conception, development of overall research plan and study oversight) contributed to statistical analyses and interpretation of the data and critically reviewed the manuscript; Petersen KS contributed to study design, planned and conducted the study, performed the data collection including vascular measurements, performed the initial statistical analyses and prepared the manuscript; Meikle PJ performed the lipid analysis and contributed to the statistical analysis and interpretation of the data and critically reviewed the manuscript; Garg ML performed the carotenoid analysis and contributed to the statistical analysis and interpretation of the data and critically reviewed the manuscript.
Institutional review board statement: Ethics approval was obtained from the University of South Australia Human Research Ethics Committee.
Informed consent statement: All participants provided written informed consent.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Peter M Clifton, PhD, Professor of Nutrition, NHMRC Principal Research Fellow, School of Pharmacy and Medical Sciences, University of South Australia, GPO Box 2471, Adelaide, SA 5000, Australia. peter.clifton@unisa.edu.au
Telephone: +61-8-84629702 Fax: +61-8-83022389
Received: July 7, 2016
Peer-review started: July 12, 2016
First decision: September 12, 2016
Revised: September 30, 2016
Accepted: November 16, 2016
Article in press: November 17, 2016
Published online: January 15, 2017
Processing time: 183 Days and 20.7 Hours
Core Tip

Core tip: This paper examines clinical, dietary and biochemical predictors of common carotid artery intima media thickness (CCA IMT) in a population of participants with type 1 and type 2 diabetes. The only predictors of CCA IMT in this group were age and body weight. After age adjustment CCA IMT was not different in subjects with type 1 or type 2 diabetes.