Mitanchez D, Yzydorczyk C, Simeoni U. What neonatal complications should the pediatrician be aware of in case of maternal gestational diabetes? World J Diabetes 2015; 6(5): 734-743 [PMID: 26069722 DOI: 10.4239/wjd.v6.i5.734]
Corresponding Author of This Article
Delphine Mitanchez, MD, PhD, Division of Neonatology, Department of Perinatology, Armand Trousseau Hospital, 26 Avenue du Docteur Arnold Netter, 75012 Paris, France. delphine.mitanchez@trs.aphp.fr
Research Domain of This Article
Pharmacology & Pharmacy
Article-Type of This Article
Minireviews
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Delphine Mitanchez, Division of Neonatology, Department of Perinatology, Armand Trousseau Hospital, 75012 Paris, France
Catherine Yzydorczyk, Umberto Simeoni, Division of Pediatrics and DOHaD Laboratory, CHUV University Hospital and UNIL, 1011 Lausanne, Switzerland
Author contributions: All the authors made substantial contributions to conception and design of the review, made critical revisions and final approval of the version of the article to be published.
Conflict-of-interest: None.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Delphine Mitanchez, MD, PhD, Division of Neonatology, Department of Perinatology, Armand Trousseau Hospital, 26 Avenue du Docteur Arnold Netter, 75012 Paris, France. delphine.mitanchez@trs.aphp.fr
Telephone: +33-1-44736191 Fax: +33-1-44736892
Received: August 28, 2014 Peer-review started: August 28, 2014 First decision: December 17, 2014 Revised: January 29, 2015 Accepted: March 16, 2015 Article in press: March 18, 2015 Published online: June 10, 2015 Processing time: 295 Days and 0.3 Hours
Core Tip
Core tip: Increased mortality and morbidity are historically attributed to neonates of diabetic mothers. A discerning analysis of the literature shows that these adverse outcomes are uncommon among infants born from “pure” gestational diabetes mellitus (GDM) mothers, well managed during pregnancy. Macrosomia is the predominant adverse outcome and the main factor linked to neonatal complications. Poor maternal glycemic control, especially in the context of maternal type 2 diabetes and obesity increases the risk of all adverse neonatal outcomes, most strikingly the risk of perinatal mortality and birth defects. Developing strategies for screening and managing women with GDM must be encouraged notably in middle and low income countries and, also to limit the adverse effects on global health population in the future.
