Shrivastav D, Kumbhakar SK, Srivastava S, Singh DD. Natural product-based treatment potential for type 2 diabetes mellitus and cardiovascular disease. World J Diabetes 2024; 15(7): 1603-1614 [PMID: PMC11292323 DOI: 10.4239/wjd.v15.i7.1603]
Corresponding Author of This Article
Desh Deepak Singh, PhD, Associate Professor, Amity Institute of Biotechnology, Amity University Rajasthan, SP-1 Kant Kalwar, RIICO Industrial Area, NH-11C, Jaipur 303002, Rajasthan, India. ddsbms@gmail.com
Research Domain of This Article
Biochemistry & Molecular Biology
Article-Type of This Article
Systematic Reviews
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Dharmsheel Shrivastav, Desh Deepak Singh, Amity Institute of Biotechnology, Amity University Rajasthan, Jaipur 303002, Rajasthan, India
Satyam Kumar Kumbhakar, Department of Biotechnology, Govt Veer Surendra Say P.G. College, Gariaband 493889, Chhattisgarh, India
Shivangi Srivastava, Department of Life Science, Chhatrapati Shahu ji Maharaj University, Kanpur 208024, Uttar Pradesh, India
Author contributions: Shrivastav D and Kumbhakar SK designed and wrote the manuscript; Srivastava S helped with information retrieval; Singh DD reviewed the data, analyzed the information, guided the inclusion of information, and provided intellectual input; and all authors approved the final version of the manuscript, all data was generated in-house, and no paper mill was used.
Conflict-of-interest statement: The authors declare that they have no conflict of interest to disclose.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Desh Deepak Singh, PhD, Associate Professor, Amity Institute of Biotechnology, Amity University Rajasthan, SP-1 Kant Kalwar, RIICO Industrial Area, NH-11C, Jaipur 303002, Rajasthan, India. ddsbms@gmail.com
Received: February 21, 2024 Revised: April 22, 2024 Accepted: May 16, 2024 Published online: July 15, 2024 Processing time: 137 Days and 22.5 Hours
Core Tip
Core Tip: This systematic review investigated the potential of natural products in the management of type 2 diabetes (T2D) and cardiovascular disease (CVD). Various natural ingredients such as American ginseng, cocoa flavanol, sesame oil, flaxseed oil, fish oil, Melissa officinalis, Terminalia chebula, Nigella sativa oil, bilberry extract have shown significantly effect on glycemic control, blood pressure management, decreased insulin sensitivity and inflammatory markers, lipid profile, endocrine and enhancement of work done. These findings suggest that natural products offer promising therapeutics for T2D and CVD applications because of their anti-inflammatory properties and anti-atherosclerotic properties, it can reduce the risk of cardiovascular complications in T2D.
