Retrospective Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. May 15, 2024; 15(5): 914-922
Published online May 15, 2024. doi: 10.4239/wjd.v15.i5.914
Associations of serum D-dimer and glycosylated hemoglobin levels with third-trimester fetal growth restriction in gestational diabetes mellitus
Ying Zhang, Teng Li, Chao-Yan Yue, Yun Liu
Ying Zhang, Chao-Yan Yue, Department of Laboratory Medicine, Obstetrics and Gynecology Hospital of Fudan University, Shanghai 200011, China
Teng Li, Department of Interventional Radiology, The People’s Hospital of Weifang City, Weifang 261041, Shandong Province, China
Yun Liu, Department of Hematology, The People’s Hospital of Weifang City, Weifang 261041, Shandong Province, China
Author contributions: Zhang Y conceived and designed the study; Liu Y guided the study; Zhang Y and Liu Y collected the clinical date; Li T and Yue CY analyzed the data; all authors drafted and revised the manuscript.
Institutional review board statement: The study was reviewed and approved by the Institutional Review Board of Obstetrics and Gynecology Hospital of Fudan University, Approval No. 2019-06.
Informed consent statement: Patients were not required to give informed consent to the study because the analysis used anonymous clinical data that were obtained after each patient agreed to treatment by written consent.
Conflict-of-interest statement: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yun Liu, MM, Doctor, Department of Hematology, The People’s Hospital of Weifang City, No. 151 Guangwen Street, Kuiwen District, Weifang 261041, Shandong Province, China. yun.1100@163.com
Received: January 5, 2024
Peer-review started: January 5, 2024
First decision: January 27, 2024
Revised: February 24, 2024
Accepted: March 15, 2024
Article in press: March 15, 2024
Published online: May 15, 2024
Processing time: 126 Days and 3.3 Hours
Core Tip

Core Tip: Pregnancy causes metabolic and immune changes, which may contribute to the development of gestational diabetes mellitus (GDM). Fetal growth restriction (FGR) is a common pregnancy complication, combined with GDM may lead to adverse perinatal outcomes, such as very low birth weight, seriously endangering perinatal life. Some serum markers may be associated with the predicted outcome. This study is to investigate the association of serum D-dimer and glycosylated hemoglobin levels with third-trimester FGR in GDM patients.