Prognostic efficacy of inflammation-based markers in patients with curative colorectal cancer resection

Table 1 Univariate and multivariate analysis of clinicopathologic variables in relation to overall survival in patients with colorectal cancer undergoing curative resection

Clinicopathologic characteristics	Univariate analysis, HR (95%CI)	P value	Multivariate analysis, HR (95%CI)	P value
Sex		0.798
Tumor location		0.685
The depth of invasion		0.877
Perineural invasion		0.931
T-stage	1.404 (1.021-1.930)	0.037
Lymph Node	0.234 (0.080-0.683)	0.037
Cancer Stage	1.173 (1.012-1.359)	0.034
CEA	1.005 (1.00-1.009)	0.042
CA19-9	1.001 (1.00-1.002)	0.040	1.001 (1.00-1.002)	0.012
NLR		0.135
LMR		0.127
PLR		0.064
PNI	0.906 (0.865-0.948)	0.001	0.938 (0.891- 0.987)	0.014

CEA: Carcinoembryonic antigen; CA19-9: Cancer antigen 19-9; NLR: Neutrophil-to-lymphocyte ratio; LMR: Lymphocyte-to-monocyte ratio; PNI: Prognostic nutritional index; PLR: Platelet-to-lymphocyte ratio.