Snail family transcriptional repressor 1 radiosensitizes esophageal cancer via epithelial-mesenchymal transition signaling: From bioinformatics to integrated study

Table 1 Correlation between Snail family transcriptional repressor 1 expression and clinicopathological parameters of 26 esophageal cancer patients

Clinicopathological factor	High (n = 13)	Low (n = 13)	χ²	P value
Gender
Male	10	11	0.2476	0.6188
Female	3	2
Age
< 70	10	13	3.391	0.0655
≥ 70	3	0
Differentiation
Well and moderately	6	10	2.6	0.1069
Poorly	7	3
Grade
I + II	3	3	0	> 0.99
III + IV	10	10
Pre-treatment status
Locally advanced + metastatic	1	7	6.5	0.0108a
Local recurrence + Recurrence with distant metastasis	12	6

^aP < 0.05.

Table 2 Parameters for the clonogenic formation assay of irradiated TE-1 and KYSE-30 cells

	NC	siSNAI1	SER
TE-1
D0	1.954	1.642	1.19
n	1.464	1.403
KYSE-30
D0	2.955	2.457	1.20
n	1.193	1.129

siSNAI1: Small interfering Snail family transcriptional repressor 1; SER: Sensitization enhancement ratio; NC: Negative control.