Copyright
©The Author(s) 2024.
World J Gastrointest Oncol. Jun 15, 2024; 16(6): 2826-2841
Published online Jun 15, 2024. doi: 10.4251/wjgo.v16.i6.2826
Published online Jun 15, 2024. doi: 10.4251/wjgo.v16.i6.2826
Table 1 Statistics of the top 10 most prolific institutions in the study of gastrointestinal tumor organoids
Rank | Affiliations | Country | Centrality | Publications |
1 | Helmholtz Association | Germany | 0.04 | 93 |
2 | Utrecht University | Netherlands | 0.03 | 85 |
3 | Utrecht University Medical Center | Netherlands | 0.03 | 81 |
4 | German Cancer Research Center (DKFZ) | Germany | 0.02 | 75 |
5 | Hubrecht Institute (KNAW) | Netherlands | 0.07 | 67 |
6 | Royal Netherlands Academy of Arts & Sciences | Netherlands | 0.06 | 66 |
7 | Harvard University | United States | 0.01 | 53 |
8 | University of California System | United States | 0.13 | 49 |
9 | UDICE-French Research Universities | France | 0.04 | 43 |
10 | Sun Yat-sen University | China | 0.11 | 40 |
Table 2 Statistics on the number of publications and total citations from the top ten journals in the field of gastrointestinal tumor organoids
Rank | Sources | Articles | Zone | H-index | Cited sources | Citations |
1 | Cancers | 83 | Q2 | 18 | Nature | 5009 |
2 | Gastroenterology | 51 | Q1 | 28 | Cell | 4009 |
3 | Oncogene | 40 | Q1 | 17 | Proceedings of the National Academy of Sciences of the United States of America | 2435 |
4 | Cancer Research | 37 | Q1 | 19 | Gastroenterology | 2399 |
5 | Scientific Reports | 36 | Q2 | 15 | Cancer Research | 2340 |
6 | Nature Communications | 35 | Q1 | 16 | Science | 2225 |
7 | Frontiers in Oncology | 33 | Q2 | 9 | Nature Medicine | 1969 |
8 | Cellular and Molecular Gastroenterology and Hepatology | 24 | Q1 | 12 | Cell Stem Cell | 1807 |
9 | Journal of Experimental & Clinical Cancer Research | 23 | Q1 | 12 | Nature Communications | 1507 |
10 | Cancer Science | 21 | Q2 | 7 | Clinical Cancer Research | 1490 |
Table 3 Statistics on the number of publications and citations of top 10 authors in the field of gastrointestinal tumor organoids
Rank | Authors | Documents | Cited author | Citations |
1 | Hans Clevers | 51 | Toshiro Sato | 1014 |
2 | Toshiro Sato | 20 | Nick Barker | 467 |
3 | David Tuveson | 15 | Marc van der Wetering | 410 |
4 | Onno Kranenburg | 15 | Jarno Drost | 387 |
5 | Masanobu Oshima | 15 | Sylvia F Boj | 320 |
6 | Owen J Sansom | 14 | Masayuki Fujii | 307 |
7 | Van der Laan | 14 | Meritxell Huch | 289 |
8 | Monique Verstegen | 13 | Georgios Vlachogiannis | 262 |
9 | Deniel Stange | 13 | Herve Tiriac | 226 |
10 | Emile Voest | 13 | Rebecca L Siegel | 226 |
Table 4 Trending topic in the field of gastrointestinal tumor organoids between 2012 and 2022
Item | Frequency | Year_q1 | Year_med | Year_q3 |
Negative regulator | 7 | 2012 | 2014 | 2020 |
Organotypic culture | 6 | 2016 | 2016 | 2019 |
Wnt receptors | 6 | 2015 | 2016 | 2018 |
Ductal pancreatic-cancer | 8 | 2017 | 2017 | 2018 |
Paneth cells | 6 | 2015 | 2017 | 2020 |
Adenomas | 5 | 2017 | 2017 | 2021 |
Lgr5 | 22 | 2016 | 2018 | 2019 |
Crypt | 20 | 2017 | 2018 | 2020 |
Epithelium | 19 | 2016 | 2018 | 2019 |
In-vitro expansion | 69 | 2018 | 2019 | 2021 |
Beta-catenin | 58 | 2017 | 2019 | 2021 |
Tumorigenesis | 51 | 2017 | 2019 | 2021 |
Expression | 296 | 2019 | 2020 | 2022 |
Stem-cells | 272 | 2019 | 2020 | 2022 |
In-vitro | 227 | 2018 | 2020 | 2022 |
Cancer | 156 | 2019 | 2021 | 2022 |
Cells | 148 | 2019 | 2021 | 2022 |
Activation | 132 | 2019 | 2021 | 2022 |
Patient-derived organoids | 31 | 2021 | 2022 | 2022 |
Metabolism | 28 | 2018 | 2022 | 2022 |
Table 5 Top ten articles with the strongest citation bursts
Strength | Tittle | Source | First author | Impact index per article1 |
46.9 | Prospective derivation of a living organoid biobank of colorectal cancer patients | Cell | Marc van de Wetering | 183.5 |
34.04 | Organoid models of human and mouse ductal pancreatic cancer | Cell | Sylvia F Boj | 132.1 |
31.15 | Long-term expansion of epithelial organoids from human colon, adenoma, adenocarcinoma, and Barrett's epithelium | Gastroenterology | Toshiro Sato | 179.2 |
21.96 | Modeling colorectal cancer using CRISPR-Cas9-mediated engineering of human intestinal organoids | Nature Medicine | Mami Matano | 81.2 |
20.92 | Sequential cancer mutations in cultured human intestinal stem cells | Nature | Jarno Drost | 76.6 |
17 | Deterministic progenitor behavior and unitary production of neurons in the neocortex | Cell | Peng Gao | 30.7 |
16.73 | Functional repair of CFTR by CRISPR/Cas9 in intestinal stem cell organoids of cystic fibrosis patients | Cell Stem Cell | Gerald Schwank | 89.8 |
16.27 | Comprehensive molecular characterization of human colon and rectal cancer | Nature | Cancer Genome Atlas Network | 507.3 |
16.04 | Oncogenic transformation of diverse gastrointestinal tissues in primary organoid culture | Nature medicine | Xingnan Li | 29.5 |
16.02 | Preserved genetic diversity in organoids cultured from biopsies of human colorectal cancer metastases | Proceedings of the National Academy of Sciences of the United States of America | Fleur Weeber | 31.1 |
- Citation: Wang G, Liu T, He WT. Visualization analysis of research hotspots and trends on gastrointestinal tumor organoids. World J Gastrointest Oncol 2024; 16(6): 2826-2841
- URL: https://www.wjgnet.com/1948-5204/full/v16/i6/2826.htm
- DOI: https://dx.doi.org/10.4251/wjgo.v16.i6.2826