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©The Author(s) 2023.
World J Gastrointest Oncol. Sep 15, 2023; 15(9): 1644-1652
Published online Sep 15, 2023. doi: 10.4251/wjgo.v15.i9.1644
Published online Sep 15, 2023. doi: 10.4251/wjgo.v15.i9.1644
Table 1 Basic information about the study patients
Age (yr) | Body mass index | White blood cell count | Platelet count | Admission creatinine (mg/dL) | |
Patients | 61.31 ± 9.60 | 24.68 ± 3.36 | 14.57 ± 3.40 | 169.55 ± 49.70 | 0.94 (0.70, 1.20) |
t/Z/χ2 values | 0.78 | 0.82 | 0.41 | 2.09 | 1.50 |
P value | > 0.05 | > 0.05 | > 0.05 | < 0.05 | > 0.05 |
Table 2 Logistics regression analysis of risk factors for multiple gastric cancers after endoscopic submucosal dissection
Clinical and lesion characteristics | OR | 95%CI | P value |
Age ≥ 65 yr | 1.902 | 0.435-8.328 | 0.393 |
Male | 1.435 | 0.383-5.382 | 0.592 |
Smoking (BI ≥ 400) | 2.697 | 0.707-10.290 | 0.146 |
Lesion in the lower third of the stomach | 11.280 | 2.720-46.775 | 0.001 |
O-shaped atrophy | 1.547 | 0.372-6.442 | 0.549 |
Severe intestinalization | 6.206 | 1.667-23.109 | 0.006 |
Divergent | 9.178 | 1.642-51.305 | 0.012 |
Table 3 Univariate analysis of risk factors for developing concurrent gastric cancer
Clinicopathological features | OR | 95%CI | P value |
Age ≥ 65 yr | 5.679 | 1.164-27.701 | 0.025 |
Male | 2.400 | 0.600-9.604 | 0.343 |
Smoking (BI ≥ 400) | 2.622 | 0.689-9.971 | 0.291 |
Family history of stomach cancer | 3.067 | 0.291-32.329 | 0.359 |
Initial multiple foci | 4.547 | 0.101-19.960 | 0.912 |
Lesion ≥ 2 cm | 2.042 | 0.563-7.399 | 0.348 |
Lesion in the lower third of the stomach | 2.469 | 0.620-9.830 | 0.220 |
O-shaped atrophy | 2.115 | 0.531-8.425 | 0.447 |
Severe intestinalization | 4.632 | 1.159-18.514 | 0.045 |
Divergent | 6.25 | 0.771-50.695 | 0.109 |
Depth of submucosal infiltration < 500 μm | 4.4 | 0.745-25.991 | 0.134 |
Table 4 Logistics regression analysis of risk factors for the development of concurrent gastric cancer
Influencing factors | OR | 95%CI | P value |
Age ≥ 65 yr | 2.458 | 0.404-14.958 | 0.329 |
Severe intestinalization | 4.711 | 0.969-22.896 | 0.055 |
Table 5 Univariate analysis of risk factors for the development of heterochronic gastric cancer
Clinicopathological features | OR | 95%CI | P value |
Age ≥ 65 yr | 7.571 | 1.606-35.699 | 0.004 |
Male | 5.400 | 1.146-25.446 | 0.022 |
Smoking (BI ≥ 400) | 3.441 | 1.056-11.214 | 0.074 |
Family history of stomach cancer | 5.111 | 0.774-33.752 | 0.123 |
Initial multiple foci | 1.813 | 0.344-9.560 | 0.831 |
Lesion ≥ 2 cm | 1.167 | 0.407-3.344 | 0.794 |
Lesion in the lower third of the stomach | 7.778 | 1.690-35.795 | 0.034 |
O-shaped atrophy | 3.437 | 0.924-12.784 | 0.061 |
Severe intestinalization | 3.821 | 1.234-11.828 | 0.047 |
Divergent | 9.375 | 1.192-73.735 | 0.037 |
Depth of submucosal infiltration < 500 μm | 1.320 | 0.144-12.089 | 0.585 |
Table 6 Logistics regression analysis of risk factors for the development of heterochronic gastric cancer
Influencing factors | OR | 95%CI | P value |
Age ≥ 65 yr | 4.119 | 0.696-24.358 | 0.119 |
Male | 4.205 | 0.882-20.057 | 0.072 |
Lesion in the lower third of the stomach | 14.87 | 2.508-88.166 | 0.003 |
Severe intestinalization | 4.484 | 1.029-19.536 | 0.046 |
Divergent | 12.644 | 1.303-122.714 | 0.029 |
- Citation: Xie B, Xia Y, Wang X, Xiong Y, Chen SB, Zhang J, He WW. Factors associated with heterochronic gastric cancer development post-endoscopic mucosal dissection in early gastric cancer patients. World J Gastrointest Oncol 2023; 15(9): 1644-1652
- URL: https://www.wjgnet.com/1948-5204/full/v15/i9/1644.htm
- DOI: https://dx.doi.org/10.4251/wjgo.v15.i9.1644