Retrospective Study
Copyright ©The Author(s) 2023.
World J Gastrointest Oncol. Dec 15, 2023; 15(12): 2093-2100
Published online Dec 15, 2023. doi: 10.4251/wjgo.v15.i12.2093
Table 1 Comparison of plasma inflammatory factor levels before and after treatment between the observation and control groups (X ± s)
Pro-adrenaline (pg/L)Cortisol (ng/L)IL-6 (ng/L)C-reactive protein (mg/L)
Control group (n = 50)Before treatment1.16 ± 0.1224.55 ± 2.5436.47 ± 1.6434.22 ± 1.64
After treatment0.88 ± 0.1821.66 ± 2.1630.08 ± 1.7227.84 ± 1.19
Observation group (n = 50)Before treatment1.15 ± 0.1924.51 ± 2.0836.39 ± 1.6634.35 ± 1.91
After treatment0.51 ± 0.0917.08 ± 1.5222.51 ± 1.5816.78 ± 1.49
t/P8.682/< 0.0015.814/< 0.00118.037/< 0.00121.122/< 0.001
t/P20.421/< 0.00119.347/< 0.00140.629/< 0.00148.655/< 0.001
t/P post-treatment inter-group values12.333/< 0.00111.632/< 0.00121.743/< 0.00138.908/< 0.001
Table 2 Comparison of perioperative indicators between the observation and the control groups (X ± s)
Group
n
Sufentanil dosage (μg)
Post-operative awakening time (min)
Postoperative time in bed (h)
Time taken for anal discharge (h)
Observation group5025.56 ± 4.5614.52 ± 1.7221.26 ± 3.4112.26 ± 1.65
Control group5071.12 ± 7.4525.62 ± 2.5130.23 ± 4.5620.17 ± 2.36
t value28.38020.5338.86115.4580.000
P value0.0000.0000.000
Table 3 Comparison of the incidence of adverse reactions between the observation and the control groups [n (%)]
LeukopeniaHepatic impairmentNausea and vomitingBone marrow suppressionRenal impairmentIncidence
Control group (n = 50)5 (11.11)3 (6.67)5 (11.11)4 (8.89)7 (15.56)24 (53.33)
Observation group (n = 50)2 (4.44)1 (2.22)1 (2.22)1 (2.22)2 (4.44)7 (15.56)
χ214.221
P value0.000