Basic Study
Copyright ©The Author(s) 2021.
World J Gastrointest Oncol. Oct 15, 2021; 13(10): 1506-1517
Published online Oct 15, 2021. doi: 10.4251/wjgo.v13.i10.1506
Table 1 Serum levels of pro-gastrin-releasing peptide and neutrophil gelatinase-associated lipocalin in tubular adenocarcinoma patients
Case
Gender
Age
Pathologic grade
pro-GRP (pg/mL)
Relative NGAL expression
NormalM64Polyps 12.32 ± 0.301 ± 0.02
P1M76Mild tubular adenocarcinoma50.02 ± 0.8010.62 ± 0.10
P2F78Mild tubular adenocarcinoma58.86 ± 1.3119.90 ± 0.22
P3F45Mild tubular adenocarcinoma50.99 ± 0.8512.17 ± 0.15
P4M74Mild tubular adenocarcinoma55.71 ± 1.1517.14 ± 0.20
P5M65Mild tubular adenocarcinoma65.87 ± 2.6122.56 ± 0.27
P6F80Mild tubular adenocarcinoma52.52 ± 1.0115.34 ± 0.19
Table 2 Serum levels of pro-gastrin-releasing peptide, neutrophil gelatinase-associated lipocalin/matrix metalloproteinase-9 in different patient groups
Group
Case
Gender
Age
Pathologic grade
pro-GRP (pg/mL)
Relative NGAL expression
Relative MMP-9 expression
NormalN-1M64--11.51 ± 0.311.00 ± 0.021.00 ± 0.01
NormalN-2M62--6.33 ± 0.130.81 ± 0.010.98 ± 0.01
NormalN-3M59--8.54 ± 0.120.93 ± 0.030.94 ± 0.02
NormalN-4M67--15.67 ± 0.371.03 ± 0.020.97 ± 0.01
NormalN-5M48--8.34 ± 0.211.12 ± 0.031.02 ± 0.02
NormalN-6M52--13.51 ± 0.330.96 ± 0.011.04 ± 0.02
NormalN-7M69--16.62 ± 0.410.89 ± 0.011.00 ± 0.01
NormalN-8M56--6.88 ± 0.221.08 ± 0.042.03 ± 0.03
NormalN-9M70--17.36 ± 0.310.97 ± 0.030.96 ± 0.01
NormalN-10M65--18.24 ± 0.351.21 ± 0.031.06 ± 0.02
II-1M54Polyps 15.68 ± 0.271.31 ± 0.021.02 ± 0.01
II-2F65Polyps 17.83 ± 0.311.42 ± 0.041.08 ± 0.02
II-3F66Polyps 20.12 ± 0.351.90 ± 0.041.28 ± 0.03
II-4M74Polyps 24.38 ± 0.462.84 ± 0.064.32 ± 0.12
II-5M65Polyps 29.67 ± 0.363.85 ± 0.072.35 ± 0.06
II-6F71Polyps 62.56 ± 0.834.24 ± 0.102.76 ± 0.07
II-7F55Polyps 38.94 ± 0.462.09 ± 0.063.00 ± 0.06
II-8M62Polyps 40.54 ± 0.525.56 ± 0.125.12 ± 0.13
II-9M64Polyps 43.86 ± 0.497.21 ± 0.163.44 ± 0.09
II-10M68Polyps 60.91 ± 0.758.23 ± 0.203.71 ± 0.11
IIII-1M68Mild tubular adenocarcinoma55.32 ± 0.463.97 ± 0.124.06 ± 0.12
IIII-2M72Mild tubular adenocarcinoma30.13 ± 0.3613.81 ± 0.234.53 ± 0.18
IIII-3F65Mild tubular adenocarcinoma52.54 ± 0.5315.06 ± 0.254.89 ± 0.20
IIII-4F70Mild tubular adenocarcinoma58.25 ± 0.495.68 ± 0.184.07 ± 0.17
IIII-5M75Mild tubular adenocarcinoma35.02 ± 0.5618.37 ± 0.294.61 ± 0.22
IIII-6M77Mild tubular adenocarcinoma61.45 ± 0.6721.35 ± 0.352.92 ± 0.15
IIII-7M65Mild tubular adenocarcinoma62.38 ± 0.7423.69 ± 0.374.82 ± 0.27
IIII-8F63Mild tubular adenocarcinoma64.43 ± 0.4824.92 ± 0.244.85 ± 0.26
IIII-9M57Mild tubular adenocarcinoma68.67 ± 0.4626.74 ± 0.305.68 ± 0.22
IIII-10M62Mild tubular adenocarcinoma70.5 ± 0.7128.32 ± 0.326.04 ± 0.17
IIIIII-1M67Severe tubular adenocarcinoma72.53 ± 0.8331.03 ± 0.266.36 ± 0.22
IIIIII-2M65Severe tubular adenocarcinoma76.27 ± 0.9637.17 ± 0.326.47 ± 0.20
IIIIII-3F80Severe tubular adenocarcinoma79.81 ± 1.1338.44 ± 0.417.53 ± 0.31
IIIIII-4F76Severe tubular adenocarcinoma84.56 ± 1.4143.68 ± 0.508.68 ± 0.25
IIIIII-5M65Severe tubular adenocarcinoma86.01 ± 1.0645.79 ± 0.554.70 ± 0.19
IIIIII-6F71Severe tubular adenocarcinoma90.12 ± 1.2849.31 ± 0.619.05 ± 0.35
IIIIII-7M66Severe tubular adenocarcinoma93.17 ± 1.3353.81 ± 0.539.52 ± 0.28
IIIIII-8M78Severe tubular adenocarcinoma94.24 ± 1.5754.68 ± 0.629.35 ± 0.34
IIIIII-9F67Severe tubular adenocarcinoma93.08 ± 1.8265.76 ± 0.729.41 ± 0.27
IIIIII-10F72Severe tubular adenocarcinoma107.38 ± 2.3485.91 ± 0.9614.84 ± 0.38