Gastric partitioning for the treatment of malignant gastric outlet obstruction

Table 1 Clinicopathological characteristics of all patients

Variables	GP, n = 30	GJ, n = 30	P value
Gender			0.405
Female	8 (26.7)	11 (36.7)
Male	22 (73.3)	19 (63.3)
Age in yr			0.343
mean (SD)	67.5 (13.4)	64.3 (12.7)
Hemoglobin in g/dL			0.782
mean (SD)	9.7 (2.1)	9.9 (1.8)
Albumin in g/dL			0.087
mean (SD)	3.6 (0.6)	3.3 (0.6)
Karnofsky performance status			0.001
60-70	20 (66.7)	7 (23.3)
80-90	10 (33.3)	23 (76.7)
ECOG			0.020
0-1	11 (36.7)	20 (66.7)
2-3	19 (67.9)	10 (33.3)
Peritoneal metastasis			0.055
P0	17 (60.7)	9 (34.6)
P1	11 (39.3)	17 (65.4)
Distant metastasis			0.192
M0	16 (57.1)	12 (40)
M1	12 (42.9)	18 (60)
Weight in Kg			0.598
mean (SD)	56.5 (12.1)	54.9 (11.3)
BMI in Kg/m²			0.362
mean (SD)	21.8 (5.1)	20.7 (3.9)
Initial GOOS			1.0
0-1	18 (60)	18 (60)
2-3	12 (40)	12 (40)

Total population n = 60. Data presented as n (%). BMI: Body mass index; ECOG: Eastern cooperative oncology group; GJ: Gastrojejunostomy; GOOS: Gastric outlet obstruction score; GP: Gastric partitioning.

Table 2 Surgical outcomes

Variables	Partitioning, n = 30	GJ, n = 30	P value
Operative time in min			< 0.001
mean (SD)	161.2 (76.4)	85.2 (37.7)
Roux-en-Y reconstruction			< 0.001
No	12 (42.9)	30 (100)
Yes	16 (57.1)	0 (0)
Anastomosis			0.001
Manual	12 (42.9)	2 (6.7)
Stapler	16 (57.1)	28 (93.3)
Postoperative complication			0.254
No/minor	28 (93.3)	24 (80)
Major	2 (6.7)	6 (20)
Surgical mortality			1.0
No	28 (93.3)	27 (90)
Yes	2 (96.7)	3 (10)
Days for GOOS ≥ 1			0.375
mean (SD)	3.3 (3.2)	2.6 (1.9)
Days for GOOS ≥ 2			0.371
mean (SD)	4.7 (3.7)	4 (1.9)
Length of hospital stay in d			0.201
mean (SD)	8.6 (5.2)	11.1 (9.2)
Final GOOS			0.080
0-1	2 (6.7)	7 (24.1)
2-3	28 (93.3)	22 (75.9)

Data presented as n (%). SD: Standard deviation; GJ: Gastrojejunostomy; GOOS: Gastric outlet obstruction score.

Table 3 Control of weight after the procedure

Variables	Partitioning, n = 30	GJ, n = 30	P value
Weight-30 d1			0.391
mean (SD)	57.7 (13.4)	54.9 (11.3)
Weight 90 d1			0.132
mean (SD)	59.9 (12,7)	54.6 (10.2)
Weight-maximum			0.966
mean (SD)	56.6 (11.8)	56.8 (10.0)
Weight-final1			0.343
mean (SD)	51.9 (12.5)	53.9 (12.7)
Weight variation initial-30 d			0.343
mean (SD)	1,92	- 1.2
Weight variation initial - 90 d			0.287
mean (SD)	- 0.28	- 0.21
Weight variation 30 - 90 d			0.140
mean (SD)	- 1.52	0.5
Weight variation initial - Final			0.383
mean (SD)	- 4.9	- 2.4
Second procedure			1.0
No	26 (86.7)	26 (86.7)
Yes	4 (13.3)	4 (13.3)

¹Data not available in some cases. Data presented as n (%). GJ: Gastrojejunostomy;

Table 4 Univariate and multivariate analyses for survival - Cox regression

Variables1	Univariate			Multivariate		P value
	HR	95%CI	P value	HR	95%CI
Age 0-64 vs > 65 yr	1.05	0.59-1.87	0.866	-	-	-
Female vs Male	0.77	0.42-1.40	0.391	-	-	-
BMI ≥ 24.4 vs < 24.4	1.07	0.60-1.91	0.819	-	-	-
Initial GOOS 2-3 vs 0-1	1.31	0.73-2.34	0.363	-	-	-
Final GOOS 2-3 vs 0-1	9.42	3.67-24.20	< 0.001	8.90	3.38 - 23.43	< 0.001
GJ vs Partitioning	1.16	0.65-207	0.612	-	-	-
Major POC vs Minor/non POC	1.51	1.07-5.90	0.035	1.68	0.65 - 4.36	0.287

¹The first variable represents the reference category. HR: Hazard ratio; 95%CI: 95% confidence interval; BMI: Body mass index; GOOS: Gastric outlet obstruction score; POC: Postoperative complication.