Molecular predictive markers in tumors of the gastrointestinal tract

Figure 1 Bar chart showing the most frequently mutated genes in esophageal cancer according to catalogue of somatic mutations in cancer database. In the Y-axis the percentage of observed mutation frequency is represented. In the X-axis the most frequently mutated genes are listed. A: Top 30 mutated genes in esophageal adenocarcinoma; B: Top 30 mutated genes in esophageal squamous cell carcinoma.

Figure 2 Bar chart showing the copy number variations in esophageal cancer according to the study performed[13]. In the Y-axis the percentage of CNV frequency is represented. In the X-axis the most frequently altered genes are listed. A: Genes most commonly affected by CNV (amplification or loss) in esophageal adenocarcinoma; B: Genes most commonly affected by CNV (amplification or loss) in esophageal squamous cell carcinoma. CNV: Copy number variation.

Figure 3 Bar chart showing the most frequently mutated genes in gastric cancer according to catalogue of somatic mutations in cancer database. In the Y-axis the percentage of observed mutation frequency is represented. In the X-axis the genes are listed.

Figure 4 Copy number variation in the most important treatment targetable genes in gastric cancer. In the Y-axis the percentage of observed CNV is represented. In the X-axis the genes are listed. CNV: Copy number variation.

Figure 5 Bar chart showing the most frequently mutated genes in gastrointestinal stromal tumors according to catalogue of somatic mutations in cancer database. In the Y-axis the percentage of observed mutation frequency is represented. In the X-axis the genes are listed. GIST: Gastrointestinal stromal tumors.

Figure 6 Copy number variation in the most important treatment targetable genes in colorectal cancer. CNV: Copy number variation.