Esophageal granular cell tumors: Case report and literature review

Figure 1 A grayish-yellow uplift was seen in the esophagus 18 cm from the incisor with smooth surface under endoscope in Case 4.

Figure 2 The tumor cells were large and polygonal with granular and eosinophilic cytoplasm, and small oval nuclei. Hematoxylin and eosin staining, × 100.

Figure 3 Immunohistochemical and histochemical staining. Envision method, × 100. A: S-100 was strongly positive in tumor cells; B: CD68 was strongly positive in tumor cells; C: CD34 was negative in tumor cells, but the surrounding mesenchymal cells were positive for CD34.