Gastric gastrointestinal stromal tumor in a patient with neurofibromatosis type I presenting with anemia: A case report

Figure 1  Family history of the patient.

Figure 2 Clinical presentation of the patient. A: Multiple café-au-lait patches and cutaneous nodular masses on the abdomen; B: Multiple café-au-lait patches and cutaneous nodular masses on the back; C: Multiple café-au-lait patches and cutaneous nodular masses on the arm; D: Gastric stromal tumor with bleeding ulcer in gastroscopy.

Figure 3 Imaging manifestations of the patient. A: Huge stromal tumor in the abdominal cavity, squeezing abdominal organs; B: Cutaneous nodular masse on the abdomen; C: Subcutaneous nodule masse on the back; D: 12 months after surgery, no relapse in the tangential line and abdominal cavity.

Figure 4 Postoperative immunohistochemical results. A: Diffusely strong expression of CD117 (× 100); B: Diffusely strong expression of delay of germination 1 (× 100); C: Diffusely strong expression of CD34 (× 100); D: Diffusely strong expression of succinate dehydrogenase complex iron sulfur subunit B (× 100); E: Diffusely strong expression of Ki67 (× 100); F: Diffusely strong expression of phosphorylated histone H3 (× 100).

Figure 5  Mutation site on chromosome.

Figure 6 Intraoperative view. A: The stromal tumor is from the stomach; B: Size of stromal tumor.