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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. Mar 15, 2025; 17(3): 99304
Published online Mar 15, 2025. doi: 10.4251/wjgo.v17.i3.99304
Published online Mar 15, 2025. doi: 10.4251/wjgo.v17.i3.99304
Gastric gastrointestinal stromal tumor in a patient with neurofibromatosis type I presenting with anemia: A case report
Guang-Yang Bai, Ke-Shu Shan, Chen-Sheng Li, Department of Gastrointestinal Surgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan 250021, Shandong Province, China
Xiang-Hua Wang, Department of Hematology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan 250021, Shandong Province, China
Ming-Yang Feng, Department of Gastrointestinal Surgery, Yinan County People’s Hospital, Linyi 276399, Shandong Province, China
Yan Gao, Department of Pathology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan 250021, Shandong Province, China
Author contributions: Bai GY performed the literature search and wrote the manuscript; Shan KS reviewed the manuscript; Li CS contributed to the conception of the study; Wang XH, Feng MY, and Gao Y helped perform the analysis with constructive discussions.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ke-Shu Shan, PhD, Department of Gastrointestinal Surgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, No. 324 Jingwu Road, Jinan 250021, Shandong Province, China. sks1016@163.com
Received: July 19, 2024
Revised: November 24, 2024
Accepted: January 2, 2025
Published online: March 15, 2025
Processing time: 210 Days and 2.6 Hours
Revised: November 24, 2024
Accepted: January 2, 2025
Published online: March 15, 2025
Processing time: 210 Days and 2.6 Hours
Core Tip
Core Tip: Gastrointestinal stromal tumor (GIST) is one of the rare complications of neurofibromatosis type 1 (NF1). In NF1-related GISTs, tumors are more common in the small intestine (90%) and are rarely found in the stomach. The condition of NF1-related GIST is complex, and there is no standard treatment plan for postoperative adjuvant therapy. Postoperative regorafenib treatment was administered in this patient, and no recurrence was noted at the one-year follow-up.