Research progress on the development of hepatocyte growth factor/c-Met signaling pathway in gastric cancer: A review

Figure 1 c-Met structure and function. A: Structures of MET; B: Hepatocyte growth factor (HGF); C: PSI-MET. Created with BioRender.com (Supplementary material).

Figure 2 Timeline of the terms used and hallmarks in hepatocyte growth factor/c-MET pathway research. HGF: Hepatocyte growth factor. Created with BioRender.com (Supplementary material).

Figure 3 Role of the hepatocyte growth factor/c-MET pathway in signet ring cell carcinoma. HGF: Hepatocyte growth factor. Created with BioRender.com (Supplementary material).

Figure 4 Pharmacochemical structure targeting hepatocyte growth factor/c-Met in gastric cancer. A: Related gene mutation sites; B: Pharmacochemical structure of MET mutations. Created with BioRender.com (Supplementary material).

Figure 5 c-Met may exhibit synergistic therapeutic effects on gastric cancer. HGF: Hepatocyte growth factor. Created with BioRender.com (Supplementary material).

Figure 6 Effect of menin loss on maternally expressed 3 and c-MET expression. MEG3: Maternally expressed 3. Created with BioRender.com (Supplementary material).