Correlation analysis of interstitial maturity and prognosis of colorectal cancer: Meta-analysis

Figure 1 Flow chart of the literature screening. ¹Consider, if feasible to do so, reporting the number of records identified from each database or register searched (rather than the total number across all databases/registers). ²If automation tools were used, indicate how many records were excluded by a human and how many were excluded by automation tools.

Figure 2  Risk of bias graph of literature quality evaluation chart.

Figure 3 Results of meta-analysis between patients with immature interstitial tumor and those with maure tumor. A: Results of meta-analysis comparing relapse-free survival rate between patients with immature interstitial tumor and those with mature tumor; B: Results of meta-analysis comparing relapse-free survival rate between the intermediate tumor stromal group and the mature tumor group; C: Results of meta-analysis comparing disease-free survival rate between patients with immature tumor stroma and those with mature tumor; D: Results of meta-analysis comparing disease-free survival rate between patients with intermediate tumor stromal type and mature tumor group; E: Results of meta-analysis comparing the overall survival rate of patients with immature and mature tumors.

Figure 4 Funnel plot of literature publication bias. A: Funnel plot of publication bias in disease-free survival rate; B: Funnel plot of publication bias in overall survival rate.