Comprehensive analysis of gene mutations and mismatch repair in Chinese colorectal cancer patients

Figure 1 KRAS/NRAS/BRAF/PIK3CA mutation frequency.

Figure 2 Multivariate logistic regression analyses for KRAS, BRAF, NRAS, and PIK3CA mutation detection. A: KRAS mutation detection; B: BRAF mutation detection; C: NRAS mutation detection; D: PIK3CA mutation detection. If the odds ratio is less than 1, then the predictor is associated with KRAS, BRAF, NRAS, and PIK3CA mutation detection. OR: Odds ratio; CI: Confidence interval.

Figure 3 The mismatch repair deficiency status distributed across different histological types and driver genes. A: Different histological types; B: Different driver genes. dMMR: Deficient mismatch repair; pMMR: Proficient mismatch repair.

Figure 4 Multivariate logistic regression analyses for deficient mismatch repair detection. If the odds ratio is less than 1, then the predictor is associated with deficient mismatch repair detection. CI: Confidence interval; OR: Odds ratio; dMMR: Deficient mismatch repair; pMMR: Proficient mismatch repair; Tis: Carcinoma in situ.