Burden landscape of hepatobiliary and pancreatic cancers in Chinese young adults: 30 years’ overview and forecasted trends

Figure 1 Age-and gender-related age-standardized incidence rates, age-standardized mortality rates and age-standardized disability-adjusted life years rates of hepatobiliary and pancreatic cancers in young population of China in 2019. A: The age-standardized incidence rates (ASIR) of liver cancer (LC); B: The age-standardized mortality rates (ASMR) of LC; C: The age-standardized disability-adjusted life years rates (ASDR) of LC; D: The ASIR of the gallbladder and biliary tract cancer (GBTC); E: The ASMR of GBTC; F: The ASDR of GBTC; G: The ASIR of pancreatic cancer (PC); H: The ASMR of PC; I: The ASDR of PC.

Figure 2 The age-standardized incidence rates, age-standardized mortality rates and age-standardized disability-adjusted life years rates of young patients with hepatobiliary and pancreatic cancers from 1990 to 2019. A: The age-standardized incidence rates (ASIR) of liver cancer (LC); B: The age-standardized mortality rates (ASMR) of LC; C: The age-standardized disability-adjusted life years rates (ASDR) of LC; D: The ASIR of the gallbladder and biliary tract cancer (GBTC); E: The ASMR of GBTC; F: The ASDR of GBTC; G: The ASIR of pancreatic cancer (PC); H: The ASMR of PC; I: The ASDR of PC.

Figure 3 Cluster analysis of hepatobiliary and pancreatic cancers based on estimated average percentage change data combining age-standardized incidence rates and age-standardized mortality rates across 17 countries and regions. A: Cluster analysis of liver cancer (LC) in males; B: Cluster analysis of LC in females; C: Cluster analysis of gallbladder and biliary tract cancer (GBTC) in males; D: Cluster analysis of GBTC in females; E: Cluster analysis of pancreatic cancer (PC) in males; F: Cluster analysis of PC in females. SDI: Socio-demographic index.

Figure 4 Proportion of liver cancer disability-adjusted life years and mortality in young adults attributable to risk factors across global, China, and other 15 regions in 2019. A: Risk factors of liver cancer (LC) in males; B: Risk factors of LC in females. DALYs: Disability-adjusted life years.

Figure 5 Proportion of gallbladder and biliary tract cancer disability-adjusted life years and mortality in young adults attributable to risk factors across global, China, and other 15 regions in 2019. A: Risk factors of gallbladder and biliary tract cancer (GBTC) in males; B: Risk factors of GBTC in females. DALYs: Disability-adjusted life years.

Figure 6 Proportion of pancreatic cancer disability-adjusted life years and mortality in young adults attributable to risk factors across global, China, and other 15 regions in 2019. A: Risk factors of pancreatic cancer (PC) in males; B: Risk factors of PC in females. DALYs: Disability-adjusted life years.

Figure 7 Trends in age-standardized incidence rate and age-standardized mortality rate for hepatobiliary and pancreatic cancers by gender in Chinese young adults from 1990 to 2035. A: The age-standardized incidence rate (ASIR) among male liver cancer (LC) patients; B: The age-standardized mortality rate (ASMR) among male LC patients; C: The ASIR among female LC patients; D: The ASMR among female LC patients; E: The ASIR among male gallbladder and biliary tract cancer (GBTC) patients; F: The ASMR among male GBTC patients; G: The ASIR among female GBTC patients; H: The ASMR among female GBTC patients; I: The ASIR among male pancreatic cancer (PC) patients; J: The ASMR among male PC patients; K: The ASIR among female PC patients; L: The ASMR among female PC patients.