Prognostic value of T cell immunoglobulin and mucin-domain containing-3 expression in upper gastrointestinal tract tumors: A meta-analysis

Figure 1 Flow diagram for the study selection criteria and process.

Figure 2 Meta-analysis of the association between T cell immunoglobulin and mucin-domain containing-3 expression and overall survival. Hazard ratio forest plot for the association between the T cell immunoglobulin and mucin-domain containing-3 expression and overall survival in upper gastrointestinal tract tumors.

Figure 3 Association between T cell immunoglobulin and mucin-domain containing-3 expression and clinicopathological characteristics was analyzed. Forest plots with Odds ratio (OR) and 95% confidence interval (CI) were drawn for the association of T cell immunoglobulin and mucin-domain containing-3 expression with clinicopathological characteristics. A: Sex; B: Age; C: Tumor location; D: Tumor size.

Figure 4 Association between T cell immunoglobulin and mucin-domain containing-3 expression and clinicopathological characteristics was analyzed. Forest plots of odds ratio (OR) and 95% confidence interval (CI) were performed for correlation between T cell immunoglobulin and mucin-domain containing-3 expression and Tumor staging and grade of tissue differentiation. A: T stage; B: N stage; C: TNM stage; D: Grade of tissue differentiation.

Figure 5 Assessment of publication bias and sensitivity analysis. A: Funnel plot that assessed the effect of potential publication bias on the meta-analysis results; B: Sensitivity analysis that evaluated the impact of omitting individual studies on the pooled effect size estimate to determine the association between the T cell immunoglobulin and mucin-domain containing-3 expression and prognosis in upper gastrointestinal tumors. HR: Hazard ratio.