Prognostic and clinicopathological value of Twist expression in esophageal cancer: A meta-analysis

Figure 1 The expression of Twist in esophageal cancer (Gene expression profiling interactive analysis 2). ^aP < 0.05.

Figure 2 PRISMA flow diagram.

Figure 3 Forest plots of the association between Twist overexpression and poor overall survival and disease-free survival/relapse-free survival/progression-free survival of patients with esophageal cancer. A: Poor overall survival (OS); B: Disease-free survival/relapse-free survival/progression-free survival; C: Subgroup analysis of OS based on the detection method.

Figure 4 Forest plots showed that Twist over-expression was correlated with T stage, N stage, M stage, tumor, node and metastasis stage, and clinical stage. A: T stage; B: N stage; C: M stage; D: Tumor, node and metastasis stage; E: Clinical stage.

Figure 5 Sensitivity analysis of the association between Twist expression and overall survival.

Figure 6 The Begg’s funnel plot for overall survival.