Primary hepatic angiosarcoma manifesting as hepatic sinusoidal obstruction syndrome: A case report

Figure 1 Abdominal plain computed tomography and contrast-enhanced computed tomography images. A: Abdominal plain computed tomography (CT) image; B: Contrast-enhanced CT image. Abdominal plain CT and contrast-enhanced CT showed hepatomegaly and splenomegaly and diffuse low-density shadows distributed in the liver and spleen. Contrast-enhanced CT revealed diffuse, hypodense, nodular or flake shadows in the liver and heterogeneous enhancement in the spleen.

Figure 2 Haematoxylin and eosin-stained liver biopsy (× 400) demonstrating significant cytological atypia with anastomosing channels.

Figure 3 Immunohistochemical staining. The hepatic angiosarcoma components are positive for CD31 and CD34 and weakly positive for electroretinography (ERG) (original magnification, × 200). A: CD31; B: CD34; C: ERG.

Figure 4 18F-fluorodeoxyglucose positron emission tomography/computed tomography images. A: 18F-fluorodeoxyglucose (¹⁸F-FDG) positron emission tomography/computed tomography (PET/CT) images show marked FDG accumulation within the liver and spleen; B: ¹⁸F-FDG PET/CT images show marked FDG accumulation within the right ilium.