Immune evasion mechanisms and therapeutic strategies in gastric cancer

doi:10.4251/wjgo.v14.i1.216

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Jan 15, 2022 (publication date) through Nov 19, 2024

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Jan 15, 2022; 14(1): 216-229
Published online Jan 15, 2022. doi: 10.4251/wjgo.v14.i1.216

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Figure 1 Overview of interactions between gastric cancer cells and various immune cells. PD-L1: Programmed death-ligand 1; TGF: Transforming growth factor; IL: Interleukin; TNF: Tumor necrosis factor; MDSC: Myeloid-derived suppressor cell; GC: Gastric cancer; NK: Natural killer; TAMs: Tumor-associated macrophages; IFN: Interferon; GZM: Granzyme; Treg: Regulatory T cell; Breg: Regulatory B cell; MMP: Matrix metalloproteinase; EGF: Epidermal growth factor.

Citation: Ma ES, Wang ZX, Zhu MQ, Zhao J. Immune evasion mechanisms and therapeutic strategies in gastric cancer. World J Gastrointest Oncol 2022; 14(1): 216-229
URL: https://www.wjgnet.com/1948-5204/full/v14/i1/216.htm
DOI: https://dx.doi.org/10.4251/wjgo.v14.i1.216