Systems-level biomarkers identification and drug repositioning in colorectal cancer

doi:10.4251/wjgo.v13.i7.638

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Jul 15, 2021 (publication date) through Apr 24, 2024

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Jul 15, 2021; 13(7): 638-661
Published online Jul 15, 2021. doi: 10.4251/wjgo.v13.i7.638

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Figure 1 An overview of systems-level biomarkers. A: An overview of systems-level biomarkers in terms of diagnostics and prognostics from a variety of “omics” levels; B: Events recorded in history for omics and drug repositioning studies. LRG1: Leucine-rich alpha-2-glycoprotein 1; EGFR: Epidermal growth factor receptor; ITIH: Inter-alpha-trypsin inhibitor heavy chain family member 4; HPX: Hemopexin; SOD: Superoxide dismutase; CRC: Colorectal cancer; TCGA: The Cancer Genome Atlas; CEA: Carcinoembryonic antigen.

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Figure 2 Drugs obtained via the drug repositioning approach in colorectal cancer.

Citation: Beklen H, Yildirim E, Kori M, Turanli B, Arga KY. Systems-level biomarkers identification and drug repositioning in colorectal cancer. World J Gastrointest Oncol 2021; 13(7): 638-661
URL: https://www.wjgnet.com/1948-5204/full/v13/i7/638.htm
DOI: https://dx.doi.org/10.4251/wjgo.v13.i7.638