Expression profiles of gastric cancer molecular subtypes in remnant tumors

doi:10.4251/wjgo.v13.i4.265

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Apr 15, 2021 (publication date) through Nov 3, 2024

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Apr 15, 2021; 13(4): 265-278
Published online Apr 15, 2021. doi: 10.4251/wjgo.v13.i4.265

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Figure 1 Results for Epstein-Barr virus infection by in situ hybridization and for microsatellite instability, E-cadherin, and p53 expression by immunohistochemistry in remnant gastric cancer and primary gastric cancer patients. A: Remnant gastric cancer; B: Primary gastric cancer. EBV: Epstein-Barr virus; MSI: Microsatellite instability; NA: No alteration.

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Figure 2 Flowchart showing the classification of molecular subtypes and final distribution. A: Remnant gastric cancer; B: Primary gastric cancer. CIN: Chromosomal instability; EBV: Epstein-Barr virus; GS: Genomically stable; ISH: In situ hybridization; MMR: Mismatch repair; MSI: Microsatellite instability.

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Figure 3 Disease-free survival and overall survival according to the subtypes of molecular classification for remnant gastric cancer and primary gastric cancer. A: Disease-free survival of primary gastric cancer; B: Disease-free survival of remnant gastric cancer; C: Overall survival of primary gastric cancer; D: Overall survival of remnant gastric cancer. CIN: Chromosomal instability; EBV: Epstein-Barr virus; GS: Genomically stable; MSI: Microsatellite instability.

Citation: Ramos MFKP, Pereira MA, Cardili L, de Mello ES, Ribeiro Jr U, Zilberstein B, Cecconello I. Expression profiles of gastric cancer molecular subtypes in remnant tumors. World J Gastrointest Oncol 2021; 13(4): 265-278
URL: https://www.wjgnet.com/1948-5204/full/v13/i4/265.htm
DOI: https://dx.doi.org/10.4251/wjgo.v13.i4.265