Colorectal cancer metastatic to the breast: A case report

Figure 1 Mass of 10 cm × 5 cm on the right breast and lymphadenopathy in the right axillary cable of about 8. 5 cm at palpation.

Figure 2 Computed tomography scan revealed coarse swelling of 11 cm × 6 cm at the right mammary level, ascending colon lesion and 3 cm lymphadenopathy. No obvious lesions on other parenchyma.

Figure 3 Microscopy examination of the breast specimen. A: Hematoxylin-Eosin: Adenocarcinoma with cribriform pattern (200 ×); B: Intense nuclear staining of the neoplastic cells for CDX2 at immunohistochemistry (× 400); and C: Microscopy examination of the breast specimen.

Figure 4 Microscopy examination of the colon specimen. A: Clusters of poorly differentiated neoplastic cells in solid and cribriform pattern and desmoplastic stromal reaction (× 100); B: Area with abundant extracellular mucin (left) (× 100); and C: CDX2 showed diffuse, nuclear positive staining in neoplastic cells (× 200).

Figure 5 Breast biopsy. A: Invasive adenocarcinoma; B: A focal cribriform pattern, necrosis area, brisk mitotic activity and muscular infiltration (arrow) (Hematoxylin-Eosin, 100 ×, 200 ×); and C: A focal cribriform pattern, necrosis area, brisk mitotic activity and muscular infiltration (arrow) (Hematoxylin-Eosin, 200 ×).