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Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. Sep 15, 2015; 7(9): 132-140
Published online Sep 15, 2015. doi: 10.4251/wjgo.v7.i9.132
Adenosquamous carcinoma of the pancreas: Molecular characterization of 23 patients along with a literature review
Erkut Borazanci, Sherri Z Millis, Ron Korn, Haiyong Han, Clifford J Whatcott, Zoran Gatalica, Michael T Barrett, Derek Cridebring, Daniel D Von Hoff
Erkut Borazanci, Daniel D Von Hoff, HonorHealth Research Institute, Virginia G. Piper Cancer Center, Scottsdale, AZ 85258, United States
Erkut Borazanci, Haiyong Han, Clifford J Whatcott, Derek Cridebring, Daniel D Von Hoff, Translational Genomics Research Institute, Phoenix, AZ 85004, United States
Sherri Z Millis, Zoran Gatalica, Caris Life Sciences, Phoenix, AZ 85040, United States
Ron Korn, Imaging Endpoints, Scottsdale, AZ 85258, United States
Michael T Barrett, Mayo Clinic, Scottsdale, AZ 85259, United States
Author contributions: All authors contributed to this paper.
Supported by In part the Lee T. Hanley Fund for Pancreatic Cancer Research.
Conflict-of-interest statement: Sherri Z Millis and Zoran Gatalica are employees with Caris and Daniel D Von Hoff also has a consulting role as Executive Director Caris Life Sciences, Scientific Advisory Board. Dr. Daniel D Von Hoff: Executive Director Caris Life Sciences, Scientific Advisory Board. Dr. Sherri Z Millis: Scientific Program Manager, Bioinformatics at Caris Life Sciences. Dr. Zoran Gatalica: medical director and pathologist at Caris Life Sciences. All remaining authors have declared no conflicts of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Dr. Erkut Borazanci, HonorHealth Research Institute, Virginia G. Piper Cancer Center, 10510 N. 92nd St. Ste 200, Scottsdale, AZ 85258, United States. erkut.borazanci@honorhealth.com
Telephone: +1-480-3231350 Fax: +1-480-3231359
Received: April 3, 2015
Peer-review started: April 3, 2015
First decision: April 27, 2015
Revised: June 26, 2015
Accepted: July 11, 2015
Article in press: July 14, 2015
Published online: September 15, 2015
Processing time: 167 Days and 2.9 Hours
Core Tip

Core tip: This analysis of 23 adenosquamous carcinoma of the pancreas in light of the reviewed literature highlights the potential to identify novel treatments when using a personalized medicine approach to patient tumor characterization.