Review
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World J Gastrointest Oncol. Jul 15, 2014; 6(7): 211-224
Published online Jul 15, 2014. doi: 10.4251/wjgo.v6.i7.211
Advances and new perspectives in the treatment of metastatic colon cancer
Gonzalo Jr Recondo, Enrique Díaz-Cantón, Máximo de la Vega, Martin Greco, Gonzalo Sr Recondo, Matias E Valsecchi
Enrique Díaz-Cantón, Máximo de la Vega, Martin Greco, Gonzalo Recondo Jr, Gonzalo Recondo Sr, Department of Medical Oncology, Centro de Educación Médica e Investigaciones Clínicas (CEMIC), Buenos Aires 1431, Argentina
Enrique Díaz-Cantón, Máximo de la Vega, Fundaleu, Fundación para combatir la Leucemia, Servicio de Oncología Clínica, Buenos Aires 1114, Argentina
Matias E Valsecchi, Depatment of Medical Oncology, Huntington Internal Medicine Group, Huntington, WV 25705, United States
Author contributions: Recondo G Jr, Díaz-Cantón E, de la Vega M and Valsecchi ME conceived the topic, contributed to the writing and revising, and provided overall design and execution of the manuscript; Greco M and Recondo G Sr contributed to the writing and revising the manuscript.
Correspondence to: Matias E Valsecchi, MD, MS, Depatment of Medical Oncology, Huntington Internal Medicine Group, 5170 U.S Route 60 East, Huntington, WV 25705, United States. meval78@yahoo.com
Telephone: +1-304-3994647 Fax: +1-304-3992390
Received: November 28, 2013
Revised: March 4, 2014
Accepted: May 29, 2014
Published online: July 15, 2014
Processing time: 229 Days and 0.2 Hours
Core Tip

Core tip: This manuscript is a comprehensive review, with the most updated information up to 2014, regarding metastatic colon cancer. It summarizes all those relevant clinical trials that constitute the theoretical framework to support our daily practice and provides rational answers to common clinical dilemmas. Additionally, it gives the reader a compilation of potential new agents that are currently being tested and may soon become the next step in the battle against this disease.