Saad N, Alsibai A, Hadid TH. Carcinomatous meningitis due to gastric adenocarcinoma: A rare presentation of relapse. World J Gastrointest Oncol 2014; 6(12): 450-453 [PMID: 25516779 DOI: 10.4251/wjgo.v6.i12.450]
Corresponding Author of This Article
Nibal Saad, MD, Resident Physician, Department of Internal Medicine, St. John Hospital and Medical Center, 19251 Mack Ave, Suite 335, Grosse Pointe Woods, MI 48236,United States. nibalsaad@yahoo.com
Research Domain of This Article
Oncology
Article-Type of This Article
Case Report
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World J Gastrointest Oncol. Dec 15, 2014; 6(12): 450-453 Published online Dec 15, 2014. doi: 10.4251/wjgo.v6.i12.450
Carcinomatous meningitis due to gastric adenocarcinoma: A rare presentation of relapse
Nibal Saad, Ahmad Alsibai, Tarik H Hadid
Nibal Saad, Ahmad Alsibai, Department of Internal Medicine, St. John Hospital and Medical Center, Detroit, MI 48236, United States
Tarik H Hadid, Department of internal medicine, Division of oncology, St. John Hospital and Medical Center, Detroit, MI 48236, United States
Author contributions: Saad N researched/reviewed the current literature and wrote the paper; Alsibai A provided the images and reviewed manuscript; Hadid TH reviewed manuscript and gave the final approval of the version to be published.
Correspondence to: Nibal Saad, MD, Resident Physician, Department of Internal Medicine, St. John Hospital and Medical Center, 19251 Mack Ave, Suite 335, Grosse Pointe Woods, MI 48236,United States. nibalsaad@yahoo.com
Telephone: +1-313-7066607 Fax: +1-313-3437784
Received: July 3, 2014 Revised: November 5, 2014 Accepted: November 17, 2014 Published online: December 15, 2014 Processing time: 168 Days and 3.7 Hours
Core Tip
Core tip: Solid tumors rarely have leptomeningeal carcinomatosis. Gastric adenocarcinoma have been rarely reported with leptomeningeal involvement, and most of the reports have been documented in patients with Asian heritage, who have higher incidence of gastric adenocarcinoma. This leptomeningeal involvement is usually a late complication of disseminated and relapsed disease. In this case, however, we describe a patient with recurrence of gastric adenocarcinoma that presented with leptomenigeal carcinomatosis. We describe the presentation, the pertinent medical history of the patient, and the clinical outcome of the disease. We highlighted that leptomeningeal carcinomatosis can be a presentation of relapse, which is rare, and indicates a poor prognosis.