Retrospective Study
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. Jun 15, 2025; 17(6): 106603
Published online Jun 15, 2025. doi: 10.4251/wjgo.v17.i6.106603
Prognostic value of hemoglobin-to-red cell distribution width ratio and inflammation markers in colorectal cancer
Esra Zeynelgil, Yakup Duzkopru, Abdulkadir Kocanoglu, Serdar Karakaya
Esra Zeynelgil, Abdulkadir Kocanoglu, Serdar Karakaya, Department of Medical Oncology, Ankara Ataturk Sanatoryum Training and Research Hospital, Ankara 06100, Türkiye
Yakup Duzkopru, Department of Medical Oncology, Ankara Etlik City Hospital, Ankara 06170, Türkiye
Co-corresponding authors: Esra Zeynelgil and Yakup Duzkopru.
Author contributions: Zeynelgil E contributed to the study concept and design; Zeynelgil E and Duzkopru Y contributed to data collection; Karakaya S contributed to statistical analysis and interpretation; Zeynelgil E and Kocanoglu A contributed to manuscript writing; All authors contributed to critical revision and have read and approved the final version of the manuscript.
Institutional review board statement: This retrospective study was conducted in accordance with the Declaration of Helsinki and was approved by the Ethics Committee of Aksaray University (No. 2025/47). Due to the retrospective nature of the study, the requirement for informed consent was waived by the ethics committee.
Informed consent statement: Informed consent was not obtained from the participants due to the retrospective nature of the study. The requirement for informed consent was waived by the ethics committee.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest.
Data sharing statement: The data used in this study are available from the corresponding author upon reasonable request.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Esra Zeynelgil, MD, Doctor, Department of Medical Oncology, Ankara Ataturk Sanatoryum Training and Research Hospital, Kuşcağız mah. Sanatoryum Caddesi no:271 Sanatoryum e.a.h., Ankara 06100, Türkiye. esra23.05@hotmail.com
Received: March 3, 2025
Revised: March 23, 2025
Accepted: April 21, 2025
Published online: June 15, 2025
Processing time: 103 Days and 16.9 Hours
Core Tip

Core Tip: Colorectal cancer is a leading cause of cancer-related deaths. While survival can be estimated with special tests, using inexpensive and validated methods such as hemogram parameters may be beneficial for clinicians. Blood parameter scales are currently used for some cancers, but there is not enough data on colorectal cancer. Hemoglobin/red cell distribution width ratio, which combines many parameters such as nutrition and inflammation in the same ratio, may be useful in predicting overall survival.