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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. Jun 15, 2025; 17(6): 105782
Published online Jun 15, 2025. doi: 10.4251/wjgo.v17.i6.105782
Published online Jun 15, 2025. doi: 10.4251/wjgo.v17.i6.105782
Potential mechanism of Camellia luteoflora against colon adenocarcinoma: An integration of network pharmacology and molecular docking
Yu-Di Dong, Wan-Qing Liu, You-Wu Hu, Hong Zhang, Wan-Di Fang, Qing Luo, The Public Experimental Center of Medicine, Affiliated Hospital of Zunyi Medical University, Zunyi 563003, Guizhou Province, China
Xi-Ming Wu, Department of Periodontics, Suzhou Stomatological Hospital, Suzhou 215005, Jiangsu Province, China
Wan-Qing Liu, You-Wu Hu, Hong Zhang, Wan-Di Fang, Department of Pathology, Affiliated Hospital of Zunyi Medical University, Zunyi 563003, Guizhou Province, China
Qing Luo, Laboratory of Cell Engineering of Guizhou Province, Affiliated Hospital of Zunyi Medical University, Zunyi 563003, Guizhou Province, China
Author contributions: Dong YD and Luo Q designed research; Wu XM and Liu WQ contributed new reagents or analytic tools; Dong YD, Wu XM and Hu YW analyzed data; Zhang H and Fang WD performed visualization; Dong YD wrote the paper; Luo Q and Wu XM reviewed the paper. All authors have read and agreed to the published version of the manuscript.
Supported by Guizhou Provincial Basic Research Program (Natural Science), No. ZK[2023]-554; and the National Natural Science Foundation of China, No. 32360144.
Conflict-of-interest statement: The authors declare no conflicts of interest.
Data sharing statement: The data presented in this study are available on request from the corresponding author due to layout restriction.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Qing Luo, Laboratory of Cell Engineering of Guizhou Province, Affiliated Hospital of Zunyi Medical University, No. 149 Dalian Road, Huichuan District, Zunyi 563003, Guizhou Province, China. zlsysluoqing@163.com
Received: February 7, 2025
Revised: April 1, 2025
Accepted: April 17, 2025
Published online: June 15, 2025
Processing time: 127 Days and 5.5 Hours
Revised: April 1, 2025
Accepted: April 17, 2025
Published online: June 15, 2025
Processing time: 127 Days and 5.5 Hours
Core Tip
Core Tip: Camellia luteoflora is rare and only distributes in Chishui City, Guizhou Province and Luzhou City, Sichuan Province in China, which has high potential economic medicinal value. Natural products and their various derivatives have consistently played a crucial role in anti-tumor drug development. In this study, we aim to explore the active ingredients in Camellia luteoflora and comprehensively identify the pharmacological interaction network of Camellia luteoflora with colon adenocarcinoma.