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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. Apr 15, 2025; 17(4): 102085
Published online Apr 15, 2025. doi: 10.4251/wjgo.v17.i4.102085
Published online Apr 15, 2025. doi: 10.4251/wjgo.v17.i4.102085
Gastric schwannoma: Computed tomography and perigastric lymph node characteristics
Yong-Kang Mo, Li-Chun Xie, Department of Radiology, The First Affiliated Hospital of Shantou University Medical College, Shantou 515000, Guangdong Province, China
Xia-Pu Chen, Dai-Ying Lin, Zhuo-Zhi Dai, Department of Radiology, Shantou Central Hospital, Shantou 515000, Guangdong Province, China
Liang-Li Hong, Department of Pathology, The First Affiliated Hospital of Shantou University Medical College, Shantou 515000, Guangdong Province, China
Yi-Ru Hu, Clinical Research Center, Shantou Central Hospital, Shantou 515000, Guangdong Province, China
Co-corresponding authors: Li-Chun Xie and Zhuo-Zhi Dai.
Author contributions: Xie LC and Dai ZZ designed the research and provided supervision; Lin DY and Dai ZZ acquired funding; Mo YK and Chen XP collected the samples, analyzed the data, visualized the results, and drafted the original manuscript; Hong LL analyzed the data; Hu YR reviewed and edited the manuscript; All authors have read and approved the final manuscript.
Supported by the National Natural Science Foundation of China, No. 82101985.
Institutional review board statement: Ethical approval was obtained from the institutional ethics committees of the First Affiliated Hospital of Shantou University Medical College (No. B-2023-143).
Informed consent statement: The requirement for informed consent was waived by the institutional review board due to the retrospective nature of the study.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
Data sharing statement: The data are available from the corresponding authors on reasonable request.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Zhuo-Zhi Dai, PhD, Associate Professor, Department of Radiology, Shantou Central Hospital, No. 114 Waima Road, Shantou 515000, Guangdong Province, China. daistu@163.com
Received: October 8, 2024
Revised: February 5, 2025
Accepted: February 24, 2025
Published online: April 15, 2025
Processing time: 168 Days and 8.8 Hours
Revised: February 5, 2025
Accepted: February 24, 2025
Published online: April 15, 2025
Processing time: 168 Days and 8.8 Hours
Core Tip
Core Tip: This is a retrospective dual-center observational study analyzing the imaging characteristics of gastric schwannoma (GS) and their correlation with Ki-67 expression. GS predominantly occurs in middle-aged women and appears as an oval, well-defined, hypodense submucosal mass with progressive, homogeneous enhancement on contrast-enhanced computed tomography. Enlarged perigastric lymph nodes, confirmed as reactive hyperplasia, are a key distinguishing feature from gastrointestinal stromal tumors. Ki-67 expression remains low, indicating minimal proliferative activity. Although GS is benign, accurate preoperative differentiation from other submucosal tumors is crucial for appropriate management.