Tang XW, Zhou Y. Signet ring cell carcinoma of the appendix and terminal ileum: A case report. World J Gastrointest Oncol 2025; 17(4): 100526 [DOI: 10.4251/wjgo.v17.i4.100526]
Corresponding Author of This Article
Yong Zhou, MBBS, Researcher, Department of General Surgery, Jiading Hospital of Traditional Chinese Medicine, No. 222 of Bole Street, Jiading District, Shanghai 201800, China. zhouyong347@163.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Oncol. Apr 15, 2025; 17(4): 100526 Published online Apr 15, 2025. doi: 10.4251/wjgo.v17.i4.100526
Signet ring cell carcinoma of the appendix and terminal ileum: A case report
Xiao-Wen Tang, Yong Zhou
Xiao-Wen Tang, Yong Zhou, Department of General Surgery, Jiading Hospital of Traditional Chinese Medicine, Shanghai 201800, China
Author contributions: Zhou Y and Tang XW were responsible for conception and design of the research, acquisition of data, analysis and interpretation of the data, and writing of the manuscript; Zhou Y was responsible for critical revision of the manuscript for intellectual content.
Informed consent statement: Informed consent was obtained from the participant.
Conflict-of-interest statement: All of the authors had no any personal, financial, commercial, or academic conflicts of interest separately.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yong Zhou, MBBS, Researcher, Department of General Surgery, Jiading Hospital of Traditional Chinese Medicine, No. 222 of Bole Street, Jiading District, Shanghai 201800, China. zhouyong347@163.com
Received: August 19, 2024 Revised: December 16, 2024 Accepted: January 23, 2025 Published online: April 15, 2025 Processing time: 218 Days and 13.6 Hours
Core Tip
Core Tip: Signet ring cell carcinoma (SRCC) of the appendix is a rare malignant tumor, which accounts for only about 2.3% of all malignant tumors of the digestive system and 0.42% of all malignant tumors. Because of the rarity of SRCC, it is important to study its clinicopathologic features, diagnosis, and treatment methods in depth to improve patient outcomes. This case report reports an extremely rare case of SRCC of the appendix with metastases in the terminal ileum. It demonstrates the diagnosis and treatment process of this rare disease, emphasizes the importance of improving alertness to rare diseases in clinical practice, and the necessity of thorough intraoperative exploration and rapid pathological examination, which helps to more accurately determine the condition, avoid unnecessary secondary surgeries, and ensure that patients are optimally treated.
