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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. Mar 15, 2025; 17(3): 98103
Published online Mar 15, 2025. doi: 10.4251/wjgo.v17.i3.98103
Published online Mar 15, 2025. doi: 10.4251/wjgo.v17.i3.98103
Evaluation of three lymph node staging systems for prognostic prediction in gastric cancer: A systematic review and meta-analysis
Ming Cheng, Yang Yu, Takehiro Watanabe, Yutaro Yoshimoto, Sanae Kaji, Yukinori Yube, Munehisa Kaneda, Hajime Orita, Shinji Mine, You-Yong Wu, Tetsu Fukunaga, Department of Upper Gastroenterological Surgery, Juntendo University School of Medicine, Tokyo 113-8431, Japan
Ming Cheng, You-Yong Wu, Department of Gastrointestinal Surgery, The Second Affiliated Hospital of Soochow University, Suzhou 215004, Jiangsu Province, China
Yang Yu, Department of Gastrointestinal Surgery, Peking University Cancer Hospital, Beijing 100142, China
Co-first authors: Ming Cheng and Yang Yu.
Co-corresponding authors: You-Yong Wu and Tetsu Fukunaga.
Author contributions: Cheng M and Yu Y acquired, analyzed, and interpreted the data, drafted the manuscript, and approved the final manuscript; Watanabe T, Yoshimoto Y, and Kaji S revised the manuscript and approved the final manuscript; Kaneda M provided guidance on statistical analysis and support for the article’s publication fees; Mine S, Yube Y, and Orita H interpreted the data, revised the manuscript, and approved the final manuscript; Wu YY acquired and interpreted the data, and approved the final manuscript; Fukunaga T conceptualized and designed the study, critically revised the manuscript, and approved the final manuscript.
Supported by the Clinical Medical Team Introduction Program of Suzhou, No. SZYJTD201804.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Tetsu Fukunaga, MD, PhD, Chief Doctor, Department of Upper Gastroenterological Surgery, Juntendo University School of Medicine, 2-1-1 Hongo Bunkyo Ward, Tokyo 113-8431, Japan. t2fukunaga@juntendo.ac.jp
Received: June 18, 2024
Revised: November 8, 2024
Accepted: December 25, 2024
Published online: March 15, 2025
Processing time: 241 Days and 8.1 Hours
Revised: November 8, 2024
Accepted: December 25, 2024
Published online: March 15, 2025
Processing time: 241 Days and 8.1 Hours
Core Tip
Core Tip: In our study, the strength of our study lies in the simultaneous inclusion of lymph nodes stage, positive lymph node ratio, and log odds of positive lymph nodes, summarizing the hazard ratios for gastric cancer prognosis after surgery, and comparing the hazard ratios to evaluate their prognostic prediction ability. We combined data from studies with the same cutoff values and plotted Kaplan-Meier survival curves for overall survival. Comparing the relative survival differentiation rates within the stratifications of the three nodal systems.